Results 261 to 270 of about 2,927,558 (337)

NADPH Oxidase Inhibition Promotes Brain Resilience by Attenuating Tauopathy and Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
CRB‐2131, as a novel Nox inhibitor, suppresses brain oxidation, tauopathy, and neuro‐inflammation, thereby preventing death of mature neurons and promoting regeneration of immature neurons. Ultimately, this fosters a resilient brain and protects cognition.
Jihyeon Lee   +13 more
wiley   +1 more source

Painting Peptides With Antimicrobial Potency Through Deep Reinforcement Learning

open access: yesAdvanced Science, EarlyView.
AMPainter is a powerful design model for ’painting’ the antimicrobial potency on any given peptide sequence, based on the strategy of virtual directed evolution and deep reinforcement learning. Abstract In the post‐antibiotic era, antimicrobial peptides (AMPs) are considered ideal drug candidates because of their lower likelihood of inducing resistance.
Ruihan Dong, Qiushi Cao, Chen Song
wiley   +1 more source

ZnO Quantum Dots@CsPbBr3 Poly‐Heterocrystalline Film Enables High‐Performance Floating‐Gate Transistor Arrays for Edge Computing

open access: yesAdvanced Science, EarlyView.
The ZnO QDs@CsPbBr3 poly‐heterocrystalline film, featuring a semi‐coherent interface, delivers high electrical conductivity and excellent photoelectric properties. Functioning as a floating gate in photosensitive transistors, it enables high hole storage at 1 V and achieves a conductivity ratio of ≈3.57×105.
Jiajun Xu   +9 more
wiley   +1 more source

Improving phishing email detection performance through deep learning with adaptive optimization. [PDF]

open access: yesSci Rep
Hosseinzadeh M   +7 more
europepmc   +1 more source

Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes

open access: yesAdvanced Science, EarlyView.
Dynamic neural deactivation bridges traditionally distinct inhibitory mechanisms—direct inhibition and competition‐induced inhibition—revealing a common neural signature across modalities. Multimodal neuroimaging and behavioral experiments demonstrate a temporal dynamic characterized by progressive frontoparietal activation decay and enhanced sensory ...
Zhenhong He   +6 more
wiley   +1 more source

The Potential of Cognitive‐Inspired Neural Network Modeling Framework for Computer Vision

open access: yesAdvanced Science, EarlyView.
In article number 202507730, Guorun Li, Lei Liu, Yuefeng Du, and co‐workers present a cognitive modeling framework (CMF) to bridge the ‘representation gap’ and ‘conceptual gap’ between cognitive theory and vision deep neural networks (VDNNs). The research findings provide new insights and solid theoretical support for VDNN modeling inspired by ...
Guorun Li   +5 more
wiley   +1 more source

SemiLT: A Multianchor Transfer Learning Method for Cross‐Modality Cell Label Annotation from scRNA‐seq to scATAC‐seq

open access: yesAdvanced Science, EarlyView.
A multianchor transfer learning method, SemiLT, enables accurate cell label annotation in sparse scATAC‐seq data by leveraging well‐annotated scRNA‐seq references. By addressing temporal discrepancies between modalities, SemiLT improves rare cell type identification and batch correction.
Zhitong Chen   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy