Results 61 to 70 of about 1,664,752 (345)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

The role of the frontal cortex in memory: an investigation of the Von Restorff effect [PDF]

, 2014
Evidence from neuropsychology and neuroimaging indicate that the pre-frontal cortex (PFC) plays an important role in human memory. Although frontal patients are able to form new memories, these memories appear qualitatively different from those of ...
Alexander, Anat Elhalal, Anderson, Atkinson, Baldo, Becker, Bjork, Bone, Bousfield, Cattell, Craik, Daffner, Davelaar, Davelaar, Davelaar, Davelaar, Deese, Delis, Duncan, Duncan, Duncan, Eddy J. Davelaar, Elhalal, Estes, Fabiani, Fabiani, Fletcher, Frith, Gershberg, Glanzer, Glanzer, Greene, Grossberg, Grossberg, Grossberg, Haarmann, Haarmann, Howard, Howard, Hunt, Incisa della Rocchetta, Kelley, Kishiyama, Løvstad, Marius Usher, McLaughlin, Melo, Mensink, Moscovitch, Moscovitch, O'Reilly, Polyn, Polyn, Raaijmakers, Ranganath, Roediger, Savage, Sederberg, Shimamura, Shimamura, Stricker, Tulving, Van Overschelde, Von Restorff, Ward   +64 more
core   +2 more sources

DATA MINING USING RANDOM FOREST, NAÏVE BAYES, AND ADABOOST MODELS FOR PREDICTION AND CLASSIFICATION OF BENIGN AND MALIGNANT BREAST CANCER

Pilar Nusa Mandiri, 2022
This study predicts and classifies benign and malignant breast cancer using 3 classification models. The method used in this research is Random Forest, Naïve Bayes and AdaBoost.
Bahtiar Imran, Hambali Hambali, Ahmad Subki, Zaeniah Zaeniah, Ahmad Yani, Muhammad Rijal Alfian   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Scaling and super-universality in the coarsening dynamics of the 3d random field Ising model

, 2008
We study the coarsening dynamics of the three-dimensional random field Ising model using Monte Carlo numerical simulations. We test the dynamic scaling and super-scaling properties of global and local two-time observables.
Baldassarri A, Baumann F Henkel M Pleimling M, Belanger D P, Belletti F (The Janus Collaboration), Bray A J, Camille Aron, Chamon C, Chamon C, Chamon C Cugliandolo L F Fabricius G Iguain J L Weeks E R, Claudio Chamon, Cugliandolo L F, Fernández J F, Fischer K H, Fytas N G, Grinstein G, Hinrichsen H, Jaubert L D C, Komori T, Leticia F Cugliandolo, Marco Picco, Marinari E, Mayer P, Mézard M, Nattermann T, Novotny M A, Oguz E, Parsaeian A Castillo H E, Puri S, Rieger H, Sicilia A, Swift M R   +30 more
core   +3 more sources

Novel Schizophrenia Risk Gene TCF4 Influences Verbal Learning and Memory Functioning in Schizophrenia Patients [PDF]

, 2011
Background: Recently, a role of the transcription factor 4 (TCF4) gene in schizophrenia has been reported in a large genome-wide association study. It has been hypothesized that TCF4 affects normal brain development and TCF4 has been related to different
Aleman A, Anna Schuhmacher, Bogerts B, Dan Rujescu, Hans-Jürgen Möller, Heinz Häfner, Ingo Frommann, Leonhard Lennertz, Martin W. Landsberg, Michael Wagner, Petra Franke, Pitt D, Rainald Mössner, Saykin AJ, Stefánsson H, Svenja Schulze-Rauschenbach, Whyte MC, Wolfgang Gaebel, Wolfgang Maier, Wolfgang Wölwer, Wright IC   +20 more
core   +1 more source

The recall accuracy of play patterns in handball players (U-13)

E-balonmano.com: Revista de Ciencias del Deporte, 2020
The aim of the study was to address whether the skill to recall play patterns in handball was influenced by the temporal period in which those actions were perceived by the players.
Vicente Luis del Campo, Cristobal González Portillo, Jesús Morenas Martín   +2 more
doaj  

Reliability and validity of the electronic version of the Hopkins verbal learning test-revised in middle-aged and elderly Chinese people

Frontiers in Aging Neuroscience, 2023
BackgroundThe aging population is increasing, making it essential to have a standardized, convenient, and valid electronic memory test that can be accessed online for older people and caregivers. The electronic version of the Hopkins Verbal Learning Test-
Lichen Jiang, Ming Xu, Shunyao Xia, Shunyao Xia, Jiahui Zhu, Jiahui Zhu, Qi Zhou, Qi Zhou, Luoyi Xu, Chuan Shi, Chuan Shi, Daxing Wu, Daxing Wu, Daxing Wu   +13 more
doaj   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Sex differences in HIV effects on visual memory among substance-dependent individuals [PDF]

, 2016
HIV’s effects on episodic memory have not been compared systematically between male and female substance-dependent individuals. We administered the Brief Visuospatial Memory Test–Revised (BVMT–R) to 280 substance-dependent HIV+ and HIV– men and women ...
Gonzalez, Raul, Keutmann, Michael K., Maki, Pauline M., Martin, Eileen M., Rubin, Leah H., Vassileva, Jasmin   +5 more
core   +2 more sources