Results 101 to 110 of about 746,119 (304)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Dense suspension of solid particles as a new heat transfer fluid for concentrated solar thermal plants: on-sun proof of concept [PDF]

open access: yes, 2013
This paper demonstrates the capacity of dense suspensions of solid particles to transfer concentrated solar power from a tubular receiver to an energy conversion process by acting as a heat transfer fluid.
Sans, Jean-Louis   +7 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Pulse Interference Mitigation Method for BeiDou Receivers Based on Message Randomization

open access: yesRemote Sensing
In complex electromagnetic environments, especially those with pulsed interference sources, long-period pulsed interference can repeatedly disrupt the real-time data within navigation messages, preventing receivers from obtaining complete message ...
Anning Liu   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Radio Receiver

open access: yes, 2010
Radio receiver in wooden casing - from the The Betty Smithers Design Collection at Staffordshire University.
The Betty Smithers Design Collection at Staffordshire University   +1 more
core  

Design of a multi-layer infrared filtering window for upgrading the 345-650 GHz superheterodyne receiver

open access: yes上海师范大学学报. 自然科学版
To further reduce the noise temperature of the LCT (Leighton Chajnantor telescope) receiver, a new cryogenic Dewar needs to be designed. The original vacuum window no longer meets the requirements for higher sensitivity and multi-beam operation of the ...
FAN Zhaoxia   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Development of a tube receiver for a solar-hybrid microturbine system

open access: yes, 2008
Solar-hybrid microturbine systems with cogeneration offer new possibilities for the generation of electricity and heat or air conditioning. The solar receiver is an important component of such a system. For a prototype system demo project a tube receiver
Amsbeck, Lars   +4 more
core  

Receiver-operating-characteristic curve analysis for the Normal versus FFKC eyes.

open access: yes, 2020
Receiver-operating-characteristic curve analysis for the Normal versus FFKC eyes.
Shigeru Kinoshita (93123)   +9 more
core   +1 more source

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