Beyond Discrimination Metrics: A Bayesian Reinterpretation of S2,3PSA% for Individual Patient Counseling. [PDF]
Eur Urol Open SciYajima S, Yoshida S, Fujii Y.
europepmc +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Analyzing factors associated with sarcopenia in community-dwelling older adults. [PDF]
Medicine (Baltimore)Shin W, Lee MJ, Kim J.
europepmc +1 more source
Functioning of a quadrature receiver for automatic train signaling under frequency instability conditions and with a random phase of the signal carrier wave [PDF]
Р.Р. Юсупов +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A low-power VHF transceiver for airborne SAR with enhanced buried object detection using chirped signal processing. [PDF]
Sci RepSiddik Y +4 more
europepmc +1 more source
Crustal structure beneath Republic of North Macedonia based on receiver function analysis
Јасмина Најдовска +1 more
openalex +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Reinforcement Learning-Based Cloud-Aware HAPS Trajectory Optimization in Soft-Switching Hybrid FSO/RF Cooperative Transmission System. [PDF]
Sensors (Basel)Cui B, Cai S, Wang L, Zhang Z, Wang F.
europepmc +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source