Results 121 to 130 of about 509,969 (294)
A functional description of the advanced receiver [PDF]
The breadboard Advanced Receiver 2 (ARX 2) that is currently being built for future use in NASA's Deep Space Network (DSN) is described. The hybrid analog/digital receiver performs multiple functions including carrier, subcarrier, and symbol ...
Hinedi, S.
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Along the Italian peninsula adjoin two crustal domains, peri‐Tyrrhenian and Adriatic, whose boundary is not univocal in central Italy. In this area, we attempt to map the extent of the Moho in the two terrains from variations of the travel time ...
Giuliana Mele +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Lithospheric Foundering in Progress Imaged Under an Extinct Continental Arc
A long‐standing question is how felsic continental crust is differentiated from its mafic parent mantle magmas. One currently proposed fundamental mechanism is lithospheric foundering and loss of dense material into the mantle.
Vera Schulte‐Pelkum, Deborah Kilb
doaj +1 more source
Multidimentional Cheap Talk [PDF]
In this paper, we extend the cheap talk model of Crawford and Sobel (1982) to a multidimensional state space. We provide a characterization of informative equilibria.
Gilat Levy, Ronny Razin
core
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
本文综合前人在青藏高原东北缘利用不同方法不同资料得到的地震各向异性结果,对该地区断裂和应力等构造特征及分层各向异性进行了分析。结果表明,青藏高原东北缘以地壳缩短增厚变形为主,部分区域存在各向异性分层或壳内韧性层。XKS (SKS,PKS和SKKS震相的统称)分裂的快波方向整体呈NW或WNW向,与上地幔物质的流动有关。地壳的快波方向表明地壳变形会受到断裂及主压应力的影响。祁连造山带和海原断裂带的分层各向异性特征揭示了上地壳与中下地壳可能存在解耦。阿拉善地块东部至鄂尔多斯地块西部可能存在壳幔解耦现象 ...
Xinyu Xia, Yuan Gao
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source

