Results 41 to 50 of about 357,202 (156)

Generalized ROC methods for immunogenicity data analysis of vaccine phase I studies in a seropositive population

Human Vaccines & Immunotherapeutics, 2018
Immunogenicity data from phase 1 vaccine studies can be difficult to interpret, especially in seropositive populations and when multiple assays are used.
Li Yu, Mark T. Esser, Judith Falloon, Tonya Villafana, Harry Yang   +4 more
doaj   +1 more source

Comparison of Two Statistical Methods to Determine Normal Range of Androgen Hormones: K-Means Cluster Analysis and Receiver Operating Characteristic Curve

Journal of Family and Reproductive Health, 2018
Objective: To assess and compare the normal ranges of androgen hormones level, total testosterone (TT), free testosterone (FT), dehydrotestosterone (DHT), androstenedione (A4), dehydroepiandrosterone (DHEA), and dehydroepiandrosterone sulfate (DHEAS), in
Fahimeh Ramezani Tehrani, Khaled Rahmani, Ali Moradi, Seyed Ali Montazeri, Razieh Bidhendi Yarandi, Fatemeh Darabi   +5 more
doaj  

ESSENCE-Q – a first clinical validation study of a new screening questionnaire for young children with suspected neurodevelopmental problems in south Japan

Neuropsychiatric Disease and Treatment, 2016
Yuhei Hatakenaka,1,2 Elisabeth Fernell,2 Masahiko Sakaguchi,3 Hitoshi Ninomiya,3 Ichiro Fukunaga,1 Christopher Gillberg2 1Kochi Gillberg Neuropsychiatry Centre, Kochi Prefectural Medical and Welfare Centre, Kochi, Japan; 2Gillberg Neuropsychiatry Centre,
Hatakenaka Y, Fernell E, Sakaguchi M, Ninomiya H, Fukunaga I, Gillberg C   +5 more
doaj  

Diagnostic Value of Serum sST2 and MicroRNA-29a in Ovarian Cancer: A Dual-Biomarker Pilot Study

Current Issues in Molecular Biology
Ovarian cancer is frequently diagnosed at an advanced stage due to non-specific symptoms, contributing to high mortality. The limited diagnostic performance of current serum assays in early disease underscores the need for complementary circulating ...
Fatma Tuba Akdeniz, Zerrin Barut, Orcun Avsar, Selvi Duman Bakırezer, Rukset Attar, Turgay Isbir   +5 more
doaj   +1 more source

Assessing recovery from neurodegeneration in spinocerebellar ataxia 1: Comparison of in vivo magnetic resonance spectroscopy with motor testing, gene expression and histology

Neurobiology of Disease, 2015
Suppression of transgene expression in a conditional transgenic mouse model of spinocerebellar ataxia 1 (SCA1) reverses the Purkinje cell pathology and motor dysfunction that are hallmarks of SCA1.
Gülin Öz, Emily Kittelson, Döne Demirgöz, Orion Rainwater, Lynn E. Eberly, Harry T. Orr, H. Brent Clark   +6 more
doaj   +1 more source

Serum autoantibodies against a panel of 15 tumor-associated antigens in the detection of ovarian cancer

Tumor Biology, 2017
In this study, enzyme-linked immunosorbent assay has been used to examine the frequencies of serum autoantibodies against two candidate tumor-associated antigens intensively selected from the Human Protein Atlas database, in combination with 13 tumor ...
Hao Sun, Jian-Xiang Shi, Hong-Fei Zhang, Meng-Tao Xing, Pei Li, Li-Ping Dai, Cheng-Lin Luo, Xiao Wang, Peng Wang, Hua Ye, Liu-Xia Li, Jian-Ying Zhang   +11 more
doaj   +1 more source

Effect of Signal Selection in Receiver Operating Characteristics (ROC) Analysis

Japanese Journal of Radiological Technology, 2010
Selection of the signal is one of the major factors in a receiver operating characteristic (ROC) study for evaluating the diagnostic accuracy of medical imaging systems. We investigated the effect of signal selections in ROC studies which were applied to evaluate a difference between the two systems.
Takeda, Satoshi, Goto, Makoto, Maruno, Tatsuya, Honda, Takuya, Mochidome, Kousuke, Shiraishi, Junji   +5 more
openaire   +3 more sources

Receiver operating characteristic analysis using a novel combined thermal and ultrasound imaging for assessment of disease activity in rheumatoid arthritis. [PDF]

Sci Rep, 2022
Tan YK, Hong C, Li H, Allen JC, Thumboo J.   +4 more
europepmc   +1 more source

Assessment of the diagnostic significance of pentraxin-3 in conjunction with procalcitonin (PCT) and C-reactive protein (CRP) for neonatal sepsis

BMC Infectious Diseases
Objective This study aimed to compare serum levels of pentraxin-3 (PTX-3) in neonates with sepsis against those without sepsis and to assess the diagnostic value of PTX-3 in relation to conventional inflammatory markers. Methods Between June and December
Yan Jin, Shuang Guo, Yanfeng Xiao, Chunyan Yin   +3 more
doaj   +1 more source

Long non-coding RNA urothelial carcinoma–associated 1 as a tumor biomarker for the diagnosis of urinary bladder cancer

Tumor Biology, 2017
To investigate the diagnostic value of urothelial carcinoma–associated 1 as a urine biomarker in urinary bladder cancer patients by performing a comprehensive meta-analysis. A comprehensive literature search was conducted by the databases PubMed, Embase,
Zichun Wang, Xiaoxiong Wang, Daming Zhang, Yongchun Yu, Licheng Cai, Cheng Zhang   +5 more
doaj   +1 more source