Results 131 to 140 of about 380,414 (301)

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Latent Supervision: A Method for Improved Performance and Calibration of Machine Learning Classification Models in Ophthalmology

Ophthalmology Science
Purpose: Standard supervised learning assumes deterministic labels (e.g., positive or negative, present or absent), neglecting the diagnostic uncertainty inherent in clinical practice. We propose latent supervision, a novel algorithm which applies latent
Hady Yazbeck, MD, Jad Assaf, MD, Tom M. Lietman, MD, Jeremy D. Keenan, MD, John Jackson, MD, Jayashree Kalpathy-Cramer, PhD, J. Peter Campbell, MD, Xubo Song, PhD, Travis K. Redd, MD   +8 more
doaj   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

The clinical meaning of the area under a receiver operating characteristic curve for the evaluation of the performance of disease markers. [PDF]

Epidemiol Health, 2022
Parodi S, Verda D, Bagnasco F, Muselli M.   +3 more
europepmc   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

Serum metabolites as diagnostic biomarkers for preterm labor: a metabolomics-based study

BMC Pregnancy and Childbirth
Background Preterm labor is a common high-risk condition during pregnancy, but current diagnostic approaches, such as cervical length measurement and uterine contraction monitoring, lack sufficient specificity and sensitivity.
Qiuhong Yi, Hua Lai, Qin Li, Chen Wang, Xiao Zhou, Lijun Liao, Siming Xin, Feng Zhang, Xiaoming Zeng, Bicheng Yang, Jiusheng Zheng   +10 more
doaj   +1 more source

Lawton's Instrumental Activities of Daily Living for Greek-Speaking Adults with Cognitive Impairment: A Psychometric Evaluation Study with Additional Receiver Operating Characteristic Curve Analysis. [PDF]

Brain Sci, 2023
Tafiadis D, Siafaka V, Voniati L, Prentza A, Papadopoulos A, Ziavra N, Konitsiotis S.   +6 more
europepmc   +1 more source

KIPPPI Receiver Operating Characteristic (ROC) curve.

, 2013
Receiver Operating Characteristic curve for KIPPPI scales Wellbeing, Competence, Autonomy and KIPPPI Total score, relative to CBCL1.5-5 Total Problem score in the clinical range. AUC = area under the curve.
Carolien L. de Haan (297612), Ingrid Kruizinga (297611), Wilma Jansen (163315), Hein Raat (148332)   +3 more
core   +1 more source

Comparison receiver operating characteristic curve analysis (P<0.0001).

, 2020
Comparison receiver operating characteristic curve analysis ...
Bong Joo Kang (1366989), Yeong Yi An (3879025), Sung Hun Kim (3609227), Ye Won Jeon (5227889), Young Jin Suh (8566488)   +4 more
core   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source