Results 81 to 90 of about 380,414 (301)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Receiver Operating Characteristic curve.
, 2019 Receiver Operating Characteristic curve for ΔTmax with indicated cut-off score ΔTmax = 2°C, for which sensitivity (SE) is 54.6%, specificity (SP) is 88.0% and area under curve is AUC = 0.655.
Krzysztof Dudek (4345051) +5 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Receiver operating characteristic curve.
, 2017 Receiver operating characteristic curve for the prediction of chorioamnionitis using the DNI, CRP level, and lymphocyte count DNI, delta neutrophil index; CRP, C-reactive ...
Hee Young Cho (518986) +5 more
core +1 more source
, 2023 Receiver-operating characteristic curve and confusion matrices for the COVID-19 case-control classifiers using logistic regression.
Chris DeBoever (15927374) +5 more
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Accuracy of logistic models and receiver operating characteristic curves [PDF]
The accuracy of prediction is a commonly studied topic in modern statistics. The performance of a predictor is becoming increasingly more important as real-life decisions axe made on the basis of prediction.
Corbett, Philip
core
Receiver Operating Characteristic Curve Analysis.
, 2014 LF: Ligamentum flavum; ES: Epidural Space; AUC: Area under curve; CI confidence interval.Receiver Operating Characteristic Curve Analysis.
Cihun-Siyong Alex Gong (622274) +5 more
core +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source