Results 181 to 190 of about 280,956 (255)

A Multi-Center Study: Developing a Nomogram for Predicting Genetic Results of Trio-Based Whole-Exome Sequencing (Trio-WES) in Diagnosing Children with Syndromic Neurodevelopmental Disorders (s-NDDs). [PDF]

Int J Gen Med
Wu R, Qiu R, Tang D, Meng Z, Li X, Li D, Tang W.   +6 more
europepmc   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

Correction: Feasibility of cystatin C as a biomarker for AECOPD severity: a cross-sectional study integrating CAT score, mMRC grade, and GOLD stage. [PDF]

Front Med (Lausanne)
Ma H, Yan M, Liu J, Zhu C.
europepmc   +1 more source

Diagnostic Accuracy of Size‐Based Preoperative CT Assessment for Predicting Lymph Node Metastasis in Colon Cancer: A Systematic Review and Meta‐Analysis

Annals of Gastroenterological Surgery, EarlyView.
Preoperative CT based on lymph node size shows moderate accuracy for detecting nodal metastasis in colon cancer. In this meta‐analysis of 29 studies (5,634 patients), pooled sensitivity and specificity were 0.69 and 0.66. Size‐based CT alone has limited value for clinical decision‐making.
Yuji Takayama, Tomoya Shimizu, Jun Watanabe, Shimpei Ogawa, Yukihide Kanemitsu   +4 more
wiley   +1 more source

Feasibility and Psychometrics of a New Test Battery for Diagnosing Patients With Schizophrenia Spectrum Disorders. [PDF]

Cureus
Fichadia PA, Sung H, Kongala S, Weber D, Wang D, Leontieva L.   +5 more
europepmc   +1 more source

Can Machine Learning Reduce Unnecessary Surgeries? A Retrospective Analysis Using Threshold Optimization to Prevent Negative Appendectomies in Adults

Annals of Gastroenterological Surgery, EarlyView.
Threshold‐optimized machine learning models using routine clinical and laboratory data in 623 adults undergoing appendectomy. Logistic regression (AUC = 0.765) and random forest (AUC = 0.785) were the best‐performing models for appendicitis detection and complicated appendicitis prediction, respectively.
Ivan Males, Marko Kumric, Zvonimir Boban, Josip Vrdoljak, Dario Pecenkovic, Matej Ivanda, Marko Grahovac, Zenon Pogorelic, Josko Bozic   +8 more
wiley   +1 more source

Significance of Lysozyme as a Biomarker in Differentiating Tubercular Pleural Effusions From Non-tubercular Effusions. [PDF]

Cureus
G V, Gnanasoundran Sundarasamy V, Wilson J.   +2 more
europepmc   +1 more source

Lymphocyte‐C‐Reactive Protein Ratio as Promising New Marker for Predicting Surgical Site Infection in Children With Ulcerative Colitis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Surgical site infection (SSI) is a major complication after ileal pouch–anal anastomosis (IPAA) in pediatric ulcerative colitis (UC), significantly impairing quality of life. The lymphocyte‐to–C‐reactive protein ratio (LCR), a composite marker of systemic inflammation and immune/nutritional status, has emerged as a potential ...
Yuhki Koike, Koki Higashi, Yuki Sato, Yuka Nagano, Tadanobu Shimura, Takahito Kitajima, Kohei Matsushita, Yoshiki Okita, Yoshinaga Okugawa, Yuji Toiyama   +9 more
wiley   +1 more source

Serum ferritin as a potential biomarker for distinguishing advanced-stage colorectal cancer: a retrospective cohort study. [PDF]

PeerJ
Cao C, Tang F, Zhu Z, Wang F, Li J.
europepmc   +1 more source

Single‐Incision Laparoscopy‐First Strategy in Crohn's Disease: Risk Factors for Conversion and Surgical Outcomes

Annals of Gastroenterological Surgery, EarlyView.
In this retrospective study of 289 patients with Crohn's disease undergoing a single‐incision laparoscopy‐first (SILS‐first) strategy, conversion to open surgery was required in only 11.8% of cases. Fistula formation, colon resection, and smoking history were identified as independent risk factors for conversion, while postoperative complications and ...
Yuki Horio, Motoi Uchino, Yusuke Tomoo, Kentaro Nagano, Kurando Kusunoki, Ryuichi Kuwahara, Kei Kimura, Kozo Kataoka, Masataka Ikeda, Hiroki Ikeuchi   +9 more
wiley   +1 more source