Results 111 to 120 of about 3,627,751 (263)

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang   +11 more
wiley   +1 more source

Efficient Calculation of Jackknife Confidence Intervals for Rank Statistics [PDF]

open access: yes
An algorithm is presented for calculating concordance-discordance totals in a time of order N log N , where N is the number of observations, using a balanced binary search tree.
Roger Newson
core  

ROC (receiver operating characteristic) analysis.

open access: yes, 2015
1 = ocular residual astigmatism; 2 = Area under the curve; 3 = Spherical Equivalent; 4 = P value
Gisbert Richard (71493)   +6 more
core   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

open access: yesAdvanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang   +11 more
wiley   +1 more source

Analysis of factors associated with positive surgical margins and the five-year survival rate after prostate cancer resection and predictive modeling

open access: yesFrontiers in Oncology
BackgroundThis study analyzed the risk factors associated with positive surgical margins (PSM) and five-year survival after prostate cancer resection to construct a positive margin prediction model.MethodsWe retrospectively analyzed the clinical data of ...
Kai Li   +7 more
doaj   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu   +8 more
wiley   +1 more source

Validation procedures in radiological diagnostic models. Neural network and logistic regression [PDF]

open access: yes
The objective of this paper is to compare the performance of two predictive radiological models, logistic regression (LR) and neural network (NN), with five different resampling methods.
Pedro Delicado   +2 more
core  

Bending‐Resistant Intimate 3D Graphene–Metal Heterojunctions for Highly Sensitive and Robust Flexible Sensors

open access: yesAdvanced Science, EarlyView.
A reservoir‐guided silver‐nanoparticle soldering strategy is developed for bending‐resistant 3D graphene–metal heterojunctions. Controlled hot‐plate evaporation confines conductive ink within the metal reservoir, suppressing spreading and protecting the LIG interface from deformation‐induced fracture.
Saeyoung Park   +5 more
wiley   +1 more source

The receiver operating characteristic (ROC) curve

open access: yesSouthwest Respiratory and Critical Care Chronicles, 2017
Shengping Yang, Gilbert Berdine
doaj   +1 more source

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