Results 161 to 170 of about 3,627,751 (263)

Design of Photocatalytic Composite Coatings for Formaldehyde Removal Based on the Visual Effects of Wood Furniture

Advanced Science, EarlyView.
This work develops photocatalytic coatings for indoor formaldehyde removal on wood surfaces. It explores coating‐induced color variations and visual perception via eye‐tracking tests. Combined with XGBoost and Bayesian optimization, an intelligent design framework is established to guide the optimization of visually friendly wood photocatalytic ...
Xinyue Wei, Shuyuan Chen, Xinlong Zhou, Han Wang, Wei Guo, Xiaoting Niu, Wei Li, Zhen Ding, Haiyuan Chi   +8 more
wiley   +1 more source

Potential Relationship Between Macrophage Inflammatory Protein-1β and Diabetic Kidney Disease: A Multi-Model Study. [PDF]

Int J Gen Med
Jiang W, Fu Y, An C, Li J.
europepmc   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Development and validation of an explainable XGBoost model for early mortality prediction in pediatric sepsis. [PDF]

Front Pediatr
Chen HM, Wang LN, Fu YB, Hua J.
europepmc   +1 more source

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

Advanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu, Qishuai Chen, Yan Ma, Yang Liu, Xianing Dong, Wenjuan Wei, Jianxin Du, Shusheng Qiu, Maojin Tian, Peiqing Zhao   +9 more
wiley   +1 more source

Assessment of emphysema with simulated low-dose dark-field radiography. [PDF]

Eur Radiol Exp
Bast H, Schick RC, Koehler T, Gassert FT, Marka AW, Sauter AP, Renger B, Zimmermann G, Makowski MR, Pfeiffer F, Pfeiffer D.   +10 more
europepmc   +1 more source

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

Advanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao, Jinyu Cheng, Feng‐ao Wang, Chenxin Yi, Jiajun Chen, Keyue Wang, Lulu Liu, Junwei Liu, Yixue Li   +8 more
wiley   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

Machine Learning-Based Prediction of Culture-Confirmed Neonatal Sepsis in a Tertiary Neonatal Intensive Care Unit: Retrospective Cohort Study. [PDF]

JMIR Med Inform
Badran E, Al-Smadi O, Algazo LT, Al Ghazo AT, Al Anber A, Sharaqa A, Abu-Argoub L, Al Jaberi S, Alhanbali A, Yacoub T, Rihan S, Al-Jaberi H.   +11 more
europepmc   +1 more source

A Linear Regression Framework for the Receiver Operating Characteristic (ROC) Curve Analysis. [PDF]

J Biom Biostat, 2012
Zhang Z, Huang Y.
europepmc   +1 more source