Results 71 to 80 of about 14,339,649 (284)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Josip Broz Tito u ''Politici'' i ''Borbi'' februara 1969: o Kosovu i Metohiji, međunarodnim odnosima i štampi [PDF]

open access: yesIstorija 20. Veka, 2015
When Yugoslav President Josip Broz Tito have visited Belgrade based newspaper and publishing houses „Politika“ and „Borba“ in February 1969, he took advantage to present some of his remarks on some of the most important problems of Yugoslav society and ...
Slobodan Selinić
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Demographic Characteristics of the Vardar Province and Issues of Self-Identification

open access: yesEtnoantropološki Problemi, 2012
The paper analyzes the demographic structure of the south of the kingdom of Yugoslavia which was characterized by political instability, feudal heritage in economy and culture of living as well as a condition of permanent ethnic and religious antagonisms
Vladan Jovanović
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

BALANCING TRUST: YUGOSLAV COMMUNISTS AND GERMAN SOCIAL DEMOCRATS (SPD) 1950–1953 [PDF]

open access: yesIstorija 20. Veka
Yugoslav and German “questions” emerged in the early 1950s as specific issues in international politics marked by the Cold War. Through them, the strengths of the opposing blocs led by the superpowers, the USA and the USSR, were measured in various ways ...
Aleksandar V. Miletić
doaj   +1 more source

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