Results 131 to 140 of about 30,281 (256)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Reception history, biblical studies and the issue of multivalency [PDF]

open access: yes, 2018
“Reception History” is a relatively new method in biblical studies, although author argues that people have been doing this, without giving it this name, for centuries.
Gillingham, Susan, Gillingham, Susan E.
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The reception of relativity in the Netherlands

open access: yes, 2013
This article reviews the early academic and public reception of Albert Einstein's theory of relativity in the Netherlands, particularly after Arthur Eddington's eclipse experiments of 1919. Initially, not much attention was given to relativity, as it did
Maas, A.   +9 more
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Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

In Quest of the Elevated Jesus : Reflections on the Angelomorphic Christology of the Book of Revelation within its Jewish Setting

open access: yes, 2002
This study considers the New Testament as a "reception" of various antecedents, such as the Old Testament, Second Temple Judaism and Graeco-Roman culture. It explores the reception of Jesus, Paul's reception in Acts, feminist reception, reception history
Ulfgard, Håkan,
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Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

VPRS 17838 Child Case History Files

open access: yes
This series consists of Child Case History Files created and maintained at the Allambie Reception Centre (VA 5033). The files served to document and monitor the emotional, medical and intellectual development of children admitted to Allambie and provide ...

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Classical reception and children's literature: Greece, Rome and childhood transformation

open access: yes, 2018
This volume presents research on the reception of the Classical world in children's literature, from the nineteenth century to the present day. It brings together contributions from scholars in Classics, English, History of Art and Education to discuss ...

core  

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