Results 211 to 220 of about 53,933 (241)

Gut Microbiota, Insulin Resistance, and Alzheimer's Disease: A Narrative Review of Mechanistic Links and Therapeutic Perspectives. [PDF]

Int J Gen Med
Li X, Liu F, Zhu Y, Shi H.
europepmc   +1 more source

High biochemical remission rates in patients with primary biliary cholangitis treated with "triple" anticholestatic therapy. [PDF]

Hepatol Commun
Cançado GGL, Chen B, Cameron M, Houri I, Leung KK, Gulamhusein AF, Hansen B, Hirschfield GM.   +7 more
europepmc   +1 more source

Transforming growth factor beta reduces proprotein convertase subtilisin/kexin type 9 in the supernatant of hepatic stellate cells. [PDF]

World J Hepatol
Bundschuh J, Neumann M, Zimny S, Spirk M, Buechler C.   +4 more
europepmc   +1 more source

Pleiotropic immunoregulation by bile acids in pathophysiology. [PDF]

Front Immunol
Lin BS, Yin MY, Xie SA, Li P, Li X.
europepmc   +1 more source

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Farnesoid X-activated receptor antagonists from a marine sponge Spongia sp.

Bioorganic and Medicinal Chemistry Letters, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sang-Jip Nam, Jungwook Chin, Hyukjae Choi   +2 more
exaly   +4 more sources

Catabolites of Cholesterol Synthesis Pathways and Forskolin as Activators of the Farnesoid X-Activated Nuclear Receptor

Toxicology and Applied Pharmacology, 2000
The nuclear receptors are a family of transcriptional mediators that, upon activation, bind DNA and regulate gene transcription. Among these receptors, the farnesoid X-activated receptor (FXR) has recently been identified as one activated by bile acids and farnesol.
Daniel J Noonan
exaly   +4 more sources

Sterols from a soft coral, Dendronephthya gigantea as farnesoid X-activated receptor antagonists

Steroids, 2012
Three new steroids 3-oxocholest-1,22-dien-12β-ol (1), 3-oxocholest-1,4-dien-20β-ol (2), 3-oxocholest-1,4-dien-12β-ol (3), and three known steroids (20S)-20-Hydroxyergosta-1,4,24(28)-trien-3-one (4) [7a], 5α,8α-Epidioxycholesta-6,22-dien-3β-ol (5) [10] and 5-cholestene-3β,12β-diol (6) [11] were isolated from a soft coral Dendronephthya gigantea.
Dong Hwan Won, Hyukjae Choi, Heonjoong Kang   +2 more
exaly   +4 more sources

Polyhydroxylated sterols from the Indonesian soft coral Sinularia sp. and their effect on farnesoid X-activated receptor

Steroids, 2012
Chemical investigation of the Indonesian soft coral Sinularia sp. resulted in the isolation of three known (1, 2 and 7) and five new (3-6 and 8) sterols, characterized by either 24-methylcholestane or gorgostane skeletons. The stereostructures of the new compounds have been elucidated by application of HR-MS and 2D NMR techniques. The isolated steroids
Putra MY, Bavestrello G, Cerrano C, RENGA, Barbara, D'Amore C, FIORUCCI, Stefano, Fattorusso E, Taglialatela Scafati O.   +7 more
openaire   +5 more sources