Results 11 to 20 of about 348,694 (233)

An Introduction to Receptors and Receptor Disorders

open access: yesExperimental Biology and Medicine, 1979
SummaryIn the last decade reliable methods have been introduced to quantitate and characterize receptors for hormones and other biologically interesting ligands. Applied initially to hormone receptors on malignant cells and to androgen-resistant and insulin-resistant states, these methods have led to the identification of many disease processes where ...
J. Roth   +8 more
openaire   +3 more sources

Receptors | Angiotensin Receptors

open access: yes, 2021
The renin-angiotensin-aldosterone system (RAS) is a vital hormone-receptor system that regulates cardiovascular and renal functions. In this article, we discuss exciting new findings in the RAS field. Recently solved active state crystal structures of Angiotensin II type 1 (AT1R) and type 2 receptor (AT2R) helped in understanding receptor activation ...
Pardhi, Triveni R., Karnik, Sadashiva S.
openaire   +1 more source

Adenosine A1 receptor: Functional receptor-receptor interactions in the brain [PDF]

open access: yesPurinergic Signalling, 2007
Over the past decade, many lines of investigation have shown that receptor-mediated signaling exhibits greater diversity than previously appreciated. Signal diversity arises from numerous factors, which include the formation of receptor dimers and interplay between different receptors.
Sichardt, Kathrin, Nieber, Karen
openaire   +2 more sources

NAADP Receptors [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2010
Of the established Ca2+-mobilizing messengers, NAADP is arguably the most tantalizing. It is the most potent, often efficacious at low nanomolar concentrations, and its receptors undergo dramatic desensitization. Recent studies have identified a new class of calcium-release channel, the two-pore channels (TPCs), as the likely targets for NAADP ...
openaire   +5 more sources

The insulin receptor [PDF]

open access: yesThe Journal of Pediatrics, 1981
Cells are endowed with specific cognitive molecules that function as receptors for hormones, neurotransmitters, and other intercellular messengers. The receptor molecules may be present in the plasma membrane, cytoplasm, or nucleus. When occupied by the messenger, the receptor is coupled to the cellular machinery that responds to the message-bearing ...
openaire   +3 more sources

Lipoxin Receptors [PDF]

open access: yesThe Scientific World JOURNAL, 2007
Lipoxins (LXs) represent a class of arachidonic acid (AA) metabolites that carry potent immunoregulatory and anti-inflammatory properties, LXA4and LXB4being the main components of this series. LXs are generated by cooperation between 5-lipoxygenase (LO) and 12- or 15-LO during cell-cell interactions or by single cell types. LX epimers at carbon 15, the
ROMANO, Mario   +2 more
openaire   +4 more sources

A Remodelação do Sistema Nervoso Autônomo Cardíaco pode Desempenhar um Papel na Fibrilação Atrial: Um Estudo do Sistema Nervoso Autônomo e Receptores Miocárdicos

open access: yesArquivos Brasileiros de Cardiologia, 2021
Resumo Fundamento Alterações do substrato elétrico e anatômico do coração são fatores que originam e perpetuam a fibrilação atrial (FA), porém, os mecanismos envolvidos não foram totalmente elucidados ainda. Objetivo: Avaliar o papel do remodelamento do
Ítalo Martins de Oliveira   +5 more
doaj   +2 more sources

P2 purinoceptors signaling in fibroblasts of rat subcutaneous tissue [PDF]

open access: yes, 2011
Mestrado em Biologia Molecular e CelularO tecido conjuntivo parece estar envolvido na génese de diversas condições patológicas. O aumento da rigidez do tecido conjuntivo, resultante da fibrose, pode constituir um factor importante no mecanismo patogénico
Reis, Carla Patrícia da Silva e Sousa
core   +1 more source

Partisanship, Deservingness, and the Attitudinal Policy Feedback Process for Social Policy

open access: yesPolicy Studies Journal, EarlyView.
ABSTRACT In an era of identity‐based partisan polarization, we examine whether social policies can still generate positive attitudinal feedback among beneficiaries. Drawing on nationally representative survey data, we demonstrate that partisanship conditions the policy feedback process through divergent perceptions of group deservingness.
Chris Faricy, Christopher Ellis
wiley   +1 more source

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