Results 1 to 10 of about 25,781 (107)

Cardiac Gq Receptors and Calcineurin Activation Are Not Required for the Hypertrophic Response to Mechanical Left Ventricular Pressure Overload

Frontiers in Cell and Developmental Biology, 2021
RationaleGq-coupled receptors are thought to play a critical role in the induction of left ventricular hypertrophy (LVH) secondary to pressure overload, although mechano-sensitive channel activation by a variety of mechanisms has also been proposed, and ...
Ze-Yan Yu, Ze-Yan Yu, Ze-Yan Yu, Hutao Gong, Jianxin Wu, Yun Dai, Scott H. Kesteven, Diane Fatkin, Diane Fatkin, Diane Fatkin, Boris Martinac, Boris Martinac, Robert M. Graham, Robert M. Graham, Robert M. Graham, Michael P. Feneley, Michael P. Feneley, Michael P. Feneley   +17 more
doaj   +1 more source

Relationship between oxytocin receptor gene polymorphism and hypertension in Turkish population

Revista Portuguesa de Cardiologia, 2022
Introduction and objectives: Known to play a key role in uterine contraction and milk ejection, the neuropeptide, oxytocin, has cardiovascular effects.
Merve M. Cicekliyurt, Begum Dermenci
doaj   +1 more source

Cardioprotection of controlled and cardiac-specific over-expression of A(2A)-adenosine receptor in the pressure overload. [PDF]

PLoS ONE, 2012
Adenosine binds to three G protein-coupled receptors (R) located on the cardiomyocyte (A(1)-R, A(2A)-R and A(3)-R) and provides cardiac protection during both ischemic and load-induced stress.
Eman A Hamad, Weizhong Zhu, Tung O Chan, Valerie Myers, Erhe Gao, Xue Li, Jin Zhang, Jianliang Song, Xue-Qian Zhang, Joseph Y Cheung, Walter Koch, Arthur M Feldman   +11 more
doaj   +1 more source

Extra-Intestinal Effects of C. difficile Toxin A and B: An In Vivo Study Using the Zebrafish Embryo Model

Cells, 2020
C.difficile infection (CDI) is not a merely “gut-confined” disease as toxemia could drive the development of CDI-related extra-intestinal effects.
Federica Tonon, Stefano Di Bella, Gabriele Grassi, Roberto Luzzati, Paolo Ascenzi, Alessandra di Masi, Cristina Zennaro   +6 more
doaj   +1 more source

Altered density of glomerular binding sites for atrial natriuretic factor in bile duct-ligated rats with ascites [PDF]

, 1991
The renal response to atrial natriuretic factor is blunted in cirrhosis with ascites. This might be due to alterations of renal receptors for atrial natriuretic factor.
Almeida, Arendt, Arendt, Ballermann, Cantin, Chinkers, De Léan, Epstein, Garcia, Gauquelin, Gauquelin, Gerbes, Gerbes, Gerbes, Gerbes, Gines, Kollenda, Kollenda, Kountouras, Laffi, Lang, Lowry, Maack, Misra, Morgan, Munson, Needleman, Olivera, Panos, Petrillo, Salerno, Thibault   +31 more
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Natriuretic peptides and cardiovascular damage in the metabolic syndrome. Molecular mechanisms and clinical implications [PDF]

, 2010
Natriuretic peptides are endogenous antagonists of vasoconstrictor and salt- and water-retaining systems in the body's defence against blood pressure elevation and plasma volume expansion, through direct vasodilator, diuretic and natriuretic properties ...
ALONZO, ALESSANDRO, Rossi C, RUBATTU, Speranza Donatella, SAVOIA, Carmine, VOLPE, Massimo   +4 more
core   +1 more source

Synergistic cardiac pathological hypertrophy induced by high-salt diet in IGF-IIRα cardiac-specific transgenic rats.

PLoS ONE, 2019
Stress-induced cardiac hypertrophy leads to heart failure. Our previous studies demonstrate that insulin-like growth factor-II receptor (IGF-IIR) signaling is pivotal to hypertrophy regulation.
Ruey-Lin Chang, Srinivasan Nithiyanantham, Chih-Yang Huang, Pei-Ying Pai, Tung-Ti Chang, Lai-Chin Hu, Ray-Jade Chen, V VijayaPadma, Wei-Wen Kuo, Chih-Yang Huang   +9 more
doaj   +1 more source

Multiplicity of cerebrospinal fluid functions: New challenges in health and disease

Cerebrospinal Fluid Research, 2008
This review integrates eight aspects of cerebrospinal fluid (CSF) circulatory dynamics: formation rate, pressure, flow, volume, turnover rate, composition, recycling and reabsorption.
Stopa Edward G, Brinker Thomas, Klinge Petra M, Duncan John A, Johanson Conrad E, Silverberg Gerald D   +5 more
doaj   +1 more source

Role of the liver in splanchnic extraction of atrial natriuretic factor in the rat [PDF]

, 1992
Mesenteric, hepatic and splanchnic extraction of C-terminal and N-terminal atrial natriuretic factor was investigated in male Sprague-Dawley rats. Plasma concentrations (mean ± S.E.M.) of C-terminal atrial natriuretic factor were 55.0 ± 6.1 fmol/ml, 31.2
Alexander L. Gerbes, Arendt, Casado, Crozier, De Bold, Dieter Jüngst, Epstein, Gaétan Thibault, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gines, Gutkowska, Henriksen, Henriksen, Hollister, Inagami, Johnson, Krieter, Krieter, Kurusawa, Lang, Laragh, Manfred Bilzer, Masuda, Moreau, Nair, Needleman, Rochus Witthaut, Schütten, Sundsfjord, Tamburini, Thibault, Veit Gülberg, Veseley, Vierhapper, Vollmar, Widimsky   +39 more
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Atrial Natriuretic Peptide, a Regulator of Nuclear Factor-κB Activation in Vivo [PDF]

, 2007
Natriuretic peptides (NPs) comprise a family of vasoactive hormones that play important roles in the regulation of cardiovascular and renal homeostasis.
Keller, Melanie, Kiemer, Alexandra K., Koch, Elke, Ladetzki-Baehs, Kathrin, Vollmar, Angelika M., Wendel, Albrecht, Zahler, Stefan   +6 more
core   +1 more source