Results 1 to 10 of about 11,970 (78)

Cardiac Gq Receptors and Calcineurin Activation Are Not Required for the Hypertrophic Response to Mechanical Left Ventricular Pressure Overload

open access: yesFrontiers in Cell and Developmental Biology, 2021
RationaleGq-coupled receptors are thought to play a critical role in the induction of left ventricular hypertrophy (LVH) secondary to pressure overload, although mechano-sensitive channel activation by a variety of mechanisms has also been proposed, and ...
Ze-Yan Yu   +17 more
doaj   +1 more source

Relationship between oxytocin receptor gene polymorphism and hypertension in Turkish population

open access: yesRevista Portuguesa de Cardiologia, 2022
Introduction and objectives: Known to play a key role in uterine contraction and milk ejection, the neuropeptide, oxytocin, has cardiovascular effects.
Merve M. Cicekliyurt, Begum Dermenci
doaj   +1 more source

Cardioprotection of controlled and cardiac-specific over-expression of A(2A)-adenosine receptor in the pressure overload. [PDF]

open access: yesPLoS ONE, 2012
Adenosine binds to three G protein-coupled receptors (R) located on the cardiomyocyte (A(1)-R, A(2A)-R and A(3)-R) and provides cardiac protection during both ischemic and load-induced stress.
Eman A Hamad   +11 more
doaj   +1 more source

Extra-Intestinal Effects of C. difficile Toxin A and B: An In Vivo Study Using the Zebrafish Embryo Model

open access: yesCells, 2020
C.difficile infection (CDI) is not a merely “gut-confined” disease as toxemia could drive the development of CDI-related extra-intestinal effects.
Federica Tonon   +6 more
doaj   +1 more source

Synergistic cardiac pathological hypertrophy induced by high-salt diet in IGF-IIRα cardiac-specific transgenic rats.

open access: yesPLoS ONE, 2019
Stress-induced cardiac hypertrophy leads to heart failure. Our previous studies demonstrate that insulin-like growth factor-II receptor (IGF-IIR) signaling is pivotal to hypertrophy regulation.
Ruey-Lin Chang   +9 more
doaj   +1 more source

Multiplicity of cerebrospinal fluid functions: New challenges in health and disease

open access: yesCerebrospinal Fluid Research, 2008
This review integrates eight aspects of cerebrospinal fluid (CSF) circulatory dynamics: formation rate, pressure, flow, volume, turnover rate, composition, recycling and reabsorption.
Stopa Edward G   +5 more
doaj   +1 more source

Endurance Exercise Prevented Diabetic Cardiomyopathy through the Inhibition of Fibrosis and Hypertrophy in Rats

open access: yesReviews in Cardiovascular Medicine
Background: Exercise training could be essential in preventing pathological cardiac remodeling in diabetes. Therefore, the effects of moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT) singly or plus metformin on ...
Sadegh Shabab   +5 more
doaj   +1 more source

Role of the hypothalamic pituitary adrenal axis in the control of the response to stress and infection

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The release of adrenocorticotropin (ACTH) from the corticotrophs is controlled principally by vasopressin and corticotropin-releasing hormone (CRH). Oxytocin may augment the release of ACTH under certain conditions, whereas atrial natriuretic peptide ...
McCann S.M.   +5 more
doaj  

Serum inflammatory factors as predictors of severity and prognosis in heart failure: A cohort study. [PDF]

open access: yesMedicine (Baltimore)
Jiang Z   +13 more
europepmc   +1 more source

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