Results 91 to 100 of about 12,045 (153)

The NPR1 agonist antibody XXB750 in heart failure: a phase 2 randomized trial. [PDF]

Nat Med
Solomon SD, McMurray JJV, Felker GM, Januzzi JL, Lam CSP, Voors AA, Claggett B, Nuehrenberg TG, Rizkala AR, Koch C, Zhu W, Lefkowitz MP.   +11 more
europepmc   +1 more source

Heart‐Specific Spinal and Vagal Afferents: Transcriptomic Signatures and Optogenetically Modulated Functional Coupling With Cardiomyocytes

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Selective purification of heart‐specific spinal and vagal sensory neurons by retrograde labeling and FACS purification showed enhanced spontaneous, optogenetic, and chemically stimulated Ca2+ activity. Transcriptomic profiling identified distinct ion channel and GPCR signatures in heart‐specific sensory neurons.
T. Akgul Caglar, Y. E. Kazci, Z. B. Durdu, S. Sahoglu Goktas, S. Bay, E. Vatandaslar, M. U. Turhan, G. Ozturk, E. Cagavi   +8 more
wiley   +1 more source

Sacubitril/Valsartan Improves Functional Capacity and Reverses LV Remodeling in Obese Patients with Hypertrophic HFpEF: A Randomized Open-Label Study. [PDF]

J Clin Med
Ovchinnikov A, Potekhina A, Shchendrygina A, Svirida O, Sobolevskaya M, Blankova Z, Glezer M, Ageev F.   +7 more
europepmc   +1 more source

Heart Failure With Preserved Ejection Fraction‐Like Phenotype in Coronary Artery Disease and Obstructive Sleep Apnea: Insights From the RICCADSA Cohort

Clinical Cardiology, Volume 49, Issue 7, July 2026.
HFpEF‐like cardiac remodeling was common in patients with coronary artery disease and preserved ejection fraction. Aging and obesity emerged as the principal correlates, while the contribution of sleep‐disordered breathing severity appeared modest and closely intertwined with adiposity. ABSTRACT Background Heart failure with preserved ejection fraction
Erik Thunström, Helena Glantz, Aylin Pihtili, Yüksel Peker   +3 more
wiley   +1 more source

The Pivotal Role of Plant Derivatives and Eicosanoid Signaling Modulation in Counteracting Cardiomiopathy. [PDF]

Int J Mol Sci
Ussia S, Ritorto G, Macrì R, Serra M, Tavernese A, Altomare C, Dardano DM, Idone C, Palma E, Muscoli C, Volterrani M, Barillà F, Mollace V, Mollace R.   +13 more
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Agonist vs. Placebo and Pulmonary Decline After Open‐Heart Surgery: A Substudy of the GLORIOUS Randomised Clinical Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Postoperative pulmonary decline is an established complication of open‐heart surgery extending beyond the immediate postoperative phase. Inflammation‐mediated lung damage and ischaemia‐reperfusion injury secondary to extracorporeal circulation is a proposed pathophysiological driver. GLP‐1 receptor agonists (GLP‐1RA) have emerged as
Astrid Duus Mikkelsen, Sebastian Wiberg, Hans Henrik Lawaetz Schultz, Peter Hasse Møller‐Sørensen, Dan Høfsten, Jens Christian Nilsson, Christian Holdflod Møller, Lars Køber, Christian Hassager, Jesper Kjærgaard   +9 more
wiley   +1 more source

Right Ventricular Function and a Novel Biomarker After TAVI: Clinical Implications of IGFBP-7. [PDF]

Echocardiography
Oktay Oğul İ, Gürbüz AS, Alsancak Y, Çelik M, Düzenli MA.   +4 more
europepmc   +1 more source

An Unusual Etiology of Bayés' Syndrome: Fabry Disease

Annals of Noninvasive Electrocardiology, Volume 31, Issue 4, July 2026.
This patient with gene confirmed Fabry disease had advanced interatrial conduction block as seen on atrial‐specific vector tracing demonstrating sinus bradycardia with first‐degree AV block and sinus P‐wave terminal delay with biphasic morphology. The patient was later diagnosed with atrial fibrillation, which led to the diagnosis of Bayés' syndrome ...
Nicholas E. Kunce, Andre Silva, Mark Haigney, Adam Kisling   +3 more
wiley   +1 more source

The Anti-Apoptotic Effect of C-Type Natriuretic Peptide and the Regulation of NPPC in Porcine Ovarian Granulosa Cells. [PDF]

Int J Mol Sci
Liu X, Lu J, Zeng J, An L, Tian J, Xi G.
europepmc   +1 more source

Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular‐Kidney‐Metabolic Syndrome

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5463-5475, July 2026.
ABSTRACT Cardiovascular‐kidney‐metabolic (CKM) syndrome is defined by the pathologic interconnections between obesity, diabetes, chronic kidney disease and cardiovascular disease. An important and underrecognized pathophysiologic factor underlying CKM syndrome is obesity‐induced aldosterone excess.
Evan Zeitler, Klara R. Klein, Ildiko Lingvay, Anthony Pick, Liana K. Billings   +4 more
wiley   +1 more source