Results 151 to 160 of about 25,910 (235)

Impact of Lipid Profile Alterations on the Right Heart Function and Prognosis in Pre‐Capillary Pulmonary Hypertension Patients: A Prospective Cohort Study

open access: yesRespirology, Volume 31, Issue 2, Page 174-183, February 2026.
This study found that reduced HDL‐C correlates with impaired RV systolic function and RA strain, highlighting a mechanistic link between lipid abnormalities and right heart remodelling. Additionally, decreased HDL‐C and LDL‐C were identified as independent mortality predictors in precPH patients. Integrating lipid parameters into ESC and ESC‐CMR models
Jiajun Guo   +14 more
wiley   +1 more source

Dietary Protein Restriction Ameliorates Cardiac Inflammaging via AMPK‐ULK1‐Mediated Mitochondrial Quality Control

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Dietary protein restriction protects the aging heart in the context of obesity by limiting mitochondrial DNA leakage and suppressing cGAS–STING‐driven inflammation. Through AMPK–ULK1‐dependent mitophagy, protein restriction restores mitochondrial quality control, reduces cardiac remodeling, and preserves metabolic homeostasis during obesity‐associated ...
Wagner S. Dantas   +8 more
wiley   +1 more source

Pharmacophore‐Based Identification and Molecular Characterization of Potent Neprilysin Inhibitors: Biochemical and Therapeutic Implications for Cardiovascular Diseases

open access: yesChemical Biology &Drug Design, Volume 107, Issue 2, February 2026.
Pharmacophore‐based virtual screening and molecular dynamics identified pentagalloylglucose and tannic acid as potent, non‐toxic neprilysin inhibitors. These natural compounds demonstrated strong binding affinity and stable interactions with the catalytic Zn2+ site, offering promising leads for cardiovascular drug development. ABSTRACT Neprilysin (NEP),
Chung‐Ting Kuo   +4 more
wiley   +1 more source

Regulation of atrial natriuretic factor release in man: Effect of water immersion [PDF]

open access: yes, 1986
Arendt, Rainer M.   +6 more
core   +1 more source

Effects of SGLT2 inhibitors across the spectrum of albuminuria in cardiovascular–kidney–metabolic conditions: A pooled analysis of randomised trials

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1105-1115, February 2026.
Abstract Background Albuminuria is associated with an increased risk of cardiovascular and kidney events. Sodium glucose co‐transporter 2 inhibitors (SGLT2i) reduce albuminuria and improve kidney outcomes in patients with albuminuric chronic kidney disease (CKD).
João Pedro Ferreira   +10 more
wiley   +1 more source

Atrial natiuretic peptid in normal humans: Hemodynamic and renal effects after single and repeated bolus injection [PDF]

open access: yes, 1989
Ball, P.   +8 more
core  

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