Results 201 to 210 of about 25,910 (235)
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Receptor Regulation of Atrial Natriuretic Factor
Journal of Vascular Research, 1990Two atrial natriuretic factor (ANF) receptor subtypes are present in vascular nooth muscle cells: the B receptors (or biologically active) coupled to a guanylate cyclase ad the C receptors (clearance) representing 95% of the total number of ANF binding sites but noncoupled to a guanylate cyclase. Using binding experiments with <sup>125</sup>
P E, Chabrier +4 more
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Three immunologically similar atrial natriuretic factor receptors
Molecular and Cellular Biochemistry, 1992One of the atrial natriuretic factor (ANF) receptors is a 180 kDa protein (180 kDa mGC) which possesses the extraordinary characteristic of being bifunctional: it is both a receptor and a guanylate cyclase. In addition to the 180 kDa mGC, there exists another 120-130 kDa protein which is also bifunctional and a 120 kDa disulfide-linked dimeric cell ...
R B, Marala, R K, Sharma
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Ontogeny of ovine fetal renal atrial natriuretic factor receptors
Life Sciences, 1994Ovine fetal renal responses to ANF decrease during the last third of gestation, although circulating fetal plasma atrial natriuretic factor (ANF) levels are higher than in the maternal circulation, and do not change with gestation. This study examined whether previously reported maturational changes in fetal renal responses to ANF are due to changes in
A, Dodd +4 more
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Vascular atrial natriuretic factor receptors in spontaneously hypertensive rats
Cardiovascular Research, 1992The aim was to investigate vascular receptors for atrial natriuretic factor (ANF) in spontaneously hypertensive (SHR), Wistar-Kyoto (WKY), and Wistar rats (WR) at different ages.Relaxation and guanylate cyclase responses of blood vessels to atrial natriuretic factor were investigated, as was the binding of 125I-ANF to vascular membranes and ANF ...
E L, Schiffrin +5 more
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Atrial natriuretic factor receptors in cultured renomedullary interstitial cells
American Journal of Physiology-Cell Physiology, 1990To gain further insight on the cell types that may mediate the effects of atrial natriuretic factor (ANF) in the renal medulla, we determined the distribution and function of biological (B) and clearance (C) receptors of ANF in renomedullary interstitial cells (RMIC).
B M, Fontoura +3 more
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Physiological Role of Silent Receptors of Atrial Natriuretic Factor
Science, 1987A ring-deleted analog of atrial natriuretic factor—des[Gln 18 , Ser 19 , Gly 20 , Leu 21 , Gly 22 ] ANF 4-23 -NH 2 (C-ANF 4-23 )—binds with high ...
T, Maack +6 more
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Dopamine receptor antagonists inhibit the natriuretic response to atrial natriuretic factor (ANF)
Life Sciences, 1985The diuretic and natriuretic response of anesthetized rats to low doses of semi-purified atrial extracts or synthetic alpha-hANP was completely blocked by intravenous injection of 50 micrograms of haloperidol or chlorpromazine. Sulpiride or metoclopramide at the same doses did not show this effect. We conclude from these results that dopamine receptors,
M, Marin-Grez +3 more
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Receptors of Atrial Natriuretic Factor
Annual Review of Physiology, 1992Atrial natriuretic factor (ANF) is a polypeptide hormone that is secreted mainly by the heart atria in response to increases in atrial pressure or atrial stretch. ANF has multiple actions in the kidney that lead to increases in glomerular filtration rate and excretion of fluid and electrolytes, modulation of renal vascular resistance, decreases in ...
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Glomerular atrial natriuretic factor receptors in experimental congestive heart failure
American Journal of Physiology-Heart and Circulatory Physiology, 1993Heart failure is usually characterized by a relative insensitivity to atrial natriuretic factor (ANF). Downregulation of ANF receptors has been reported but remains controversial. Renal response to ANF infusion, glomerular ANF receptors, and guanosine 3',5'-cyclic monophosphate (cGMP) production have been studied in rabbits with congestive heart ...
R, Isnard +8 more
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Atrial Natriuretic Factor Receptor Assays
1991Publisher Summary This chapter describes the studies conducted for atrial natriuretic factor (ANF) receptor assays. Cardiac atria are believed to play an important role in the regulation of extracellular fluid volume and electrolyte homeostasis. Distension of the atrial walls or an increase in intra-atrial pressure induces water and salt excretion ...
R. Fernandez-Durango, J. Gutkowska
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