Results 211 to 220 of about 25,910 (235)
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Glomerular and vascular atrial natriuretic factor receptors in adrenalectomized rats
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1989The renal and vascular responses to atrial natriuretic factor (ANF) and glomerular and vascular ANF receptors were studied in adrenalectomized (ADR) rats with or without deoxycorticosterone (DOC) or dexamethasone (Dexa) replacement therapy. As expected, adrenalectomy elicited hypotension, hemoconcentration, and increased plasma renin activity, but no ...
V, Cachofeiro +3 more
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High affinity receptors for atrial natriuretic factor in PC12 cells
Biochemical and Biophysical Research Communications, 1988Specific receptors for atrial natriuretic factor (ANF) are characterized on PC12 cells (rat pheochromocytoma cell line). Radioiodinated synthetic ANF (Rat, 8-33) bound to a single class of high affinity binding sites with the Kd value of 6.7 X 10(-10) M.
A, Rathinavelu, G E, Isom
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Identification and Localization of Atrial Natriuretic Factor Receptors in Human Spermatozoa
Archives of Andrology, 1992Specific binding sites for atrial natriuretic factor (ANF) have been detected and localized in viable human spermatozoa through radioreceptor analysis and autoradiography, respectively. Radiotracer uptake was time and concentration dependent. Scatchard analysis of saturation data showed a single class of ANF receptors with a kd of 2.5 nM and a Bmax of ...
SILVESTRONI, Leopoldo +3 more
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Atrial natriuretic factor-receptor guanylate cyclase signal transduction mechanism
Molecular and Cellular Biochemistry, 2009Atrial natriuretic factor (ANF) receptor guanylate cyclase (ANF-RGC), like the other members of the membrane guanylate cyclase family, is a single transmembrane-spanning protein. The transmembrane domain separates the protein into two regions, extracellular and intracellular.
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Renal effects of atrial natriuretic factor are independent of dopamine1 receptors
American Journal of Physiology-Renal Physiology, 1988This study examined whether the renal effects of atrial natriuretic factor (ANF) are mediated by dopamine1 (DA1) receptor activation. Intravenous infusion of low-dose ANF (0.0025 micrograms.kg-1.min-1) in euvolemic, pentobarbital sodium-anesthetized male mongrel dogs enhanced urine flow (V) by 71 +/- 14% (mean +/- SE) and urinary sodium excretion ...
M B, Murphy, A S, Bass, L I, Goldberg
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Clearance receptor and neutral endopeptidase-mediated metabolism of atrial natriuretic factor
American Journal of Physiology-Renal Physiology, 1992A novel small linear C-atrial natriuretic factor receptor ligand [C-ANF-(11-15)] and phosphoramidon (PHO) were used to determine the effects of C-ANF receptor blockade alone, or in combination with inhibition of neutral endopeptidase (NEP), on the pharmacokinetics and metabolism of ANF in the rat.
OKOLICANY, J +4 more
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Functional properties of atrial natriuretic factor receptors.
Seminars in nephrology, 1993의과학대학원
Maack T +3 more
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Receptors for atrial natriuretic factor in cultured vascular smooth muscle cells
Life Sciences, 1986The presence of receptors for atrial natriuretic factor (ANF) was previously demonstrated in the mesenteric vascular bed in rats. Cultured vascular smooth muscle cells obtained from mesenteric arteries of rats were examined for binding of ANF. Saturation and competition experiments demonstrated the presence of a single class of receptors for ANF with ...
E L, Schiffrin +3 more
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Atrial natriuretic factor receptors on human platelets.
Cellular and molecular biology (Noisy-le-Grand, France), 1994Specific binding sites for ANF have been identified on human platelets. To determine maximal binding (Bmax) and dissociation constant (Kd), we adapted the only original method by developing a specific sequence of platelet preparation. From venous blood collected on citrated anticoagulant, platelets were prepared by successive centrifugations at 20 ...
V, Blaise +3 more
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Downregulation of renal atrial natriuretic factor receptors and receptor mRNAs during rat pregnancy
American Journal of Physiology-Renal Physiology, 1997Using renal glomeruli and papillae from virgin, pregnant (15- to 17-day), and postpartum (day 2) rats, we investigated whether the decrease in the renal effects of atrial natriuretic factor (ANF) during pregnancy is caused by a downregulation of ANF receptors.
S, Omer +4 more
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