Results 21 to 30 of about 2,510,699 (306)

Topological and Structural Plasticity of the Single Ig Fold and the Double Ig Fold Present in CD19

open access: yesBiomolecules, 2021
The Ig fold has had a remarkable success in vertebrate evolution, with a presence in over 2% of human genes. The Ig fold is not just the elementary structural domain of antibodies and TCRs, it is also at the heart of a staggering 30% of immunologic cell ...
Philippe Youkharibache
doaj   +1 more source

Secondary Structure of Corona Proteins Determines the Cell Surface Receptors Used by Nanoparticles

open access: yesJournal of Physical Chemistry B, 2014
Nanoparticles used for biological and biomedical applications encounter a host of extracellular proteins. These proteins rapidly adsorb onto the nanoparticle surface, creating a protein corona.
C. Fleischer, C. Payne
semanticscholar   +1 more source

Cell-surface translational dynamics of nicotinic acetylcholine receptors

open access: yesFrontiers in Synaptic Neuroscience, 2014
Synapse efficacy heavily relies on the number of neurotransmitter receptors available at a given time. In addition to the equilibrium between the biosynthetic production, exocytic delivery and recycling of receptors on the one hand, and the endocytic ...
Francisco J Barrantes
doaj   +1 more source

Molecular recognition of paired receptors in the immune system

open access: yesFrontiers in Microbiology, 2012
Cell surface receptors are responsible for regulating cellular function on the front line, the cell membrane. Interestingly, accumulating evidence clearly reveals that the members of cell surface receptor families have very similar extracellular ligand ...
Kimiko eKuroki   +4 more
doaj   +1 more source

Anterograde Trafficking of CXCR4 and CCR2 Receptors in a Prostate Cancer Cell Line

open access: yesCellular Physiology and Biochemistry, 2013
Background: Most prostate cancer-related deaths result from metastasis. CXCR4 and CCR2 are known to govern cellular processes resulting in cell migration, proliferation and survival.
Kelsie Gillies   +3 more
doaj   +1 more source

Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL

open access: yesFrontiers in Cell and Developmental Biology, 2021
Tumor necrosis factor-associated ligand inducing apoptosis (TRAIL) induces apoptosis through the death receptors (DRs) 4 and 5 expressed on the cell surface. Upon ligand stimulation, death receptors are rapidly internalized through clathrin-dependent and
Artem A. Artykov   +8 more
doaj   +1 more source

Signaling Pathways of Receptors Involved in Platelet Activation andShedding of These Receptors in Stored Platelets [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2019
All cells encounter various signals coming from the surrounding environment and they need toreceive and respond to these signals in order to perform their functions. Cell surface receptorsare responsible for signal transduction .Platelets are blood cells
Asra Amelirad   +3 more
doaj   +1 more source

Viral destruction of cell surface receptors [PDF]

open access: yesProceedings of the National Academy of Sciences, 2008
Viral infection is initiated by the attachment of the virus to the appropriate host cells. This process involves a series of dedicated virion proteins that have evolved to specifically recognize one, or a small number, of cell-surface molecules.
Andrew D, Mesecar, Kiira, Ratia
openaire   +2 more sources

Biomaterials-mediated ligation of immune cell surface receptors for immunoengineering

open access: yesImmuno-Oncology and Technology
A wide variety of cell surface receptors found on immune cells are essential to the body’s immunological defense mechanisms. Cell surface receptors enable immune cells to sense extracellular stimuli and identify pathogens, transmitting activating or ...
H. Cui, L. Zhang, Y. Shi
doaj   +1 more source

Calreticulin: Roles in Cell-Surface Protein Expression

open access: yesMembranes, 2014
In order to perform their designated functions, proteins require precise subcellular localizations. For cell-surface proteins, such as receptors and channels, they are able to transduce signals only when properly targeted to the cell membrane ...
Yue Jiang   +2 more
doaj   +1 more source

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