Topological and Structural Plasticity of the Single Ig Fold and the Double Ig Fold Present in CD19
Biomolecules, 2021 The Ig fold has had a remarkable success in vertebrate evolution, with a presence in over 2% of human genes. The Ig fold is not just the elementary structural domain of antibodies and TCRs, it is also at the heart of a staggering 30% of immunologic cell ...
Philippe Youkharibache
doaj +1 more source
The trafficking and targeting of P2X receptors [PDF]
, 2013 The functional expression of P2X receptors at the plasma membrane is dependent on their trafficking along secretory and endocytic pathways. There are seven P2X receptor subunits, and these differ in their subcellular distributions because they have very ...
Murrell-Lagnado, Ruth D +1 more
core +3 more sources
Cell-surface translational dynamics of nicotinic acetylcholine receptors
Frontiers in Synaptic Neuroscience, 2014 Synapse efficacy heavily relies on the number of neurotransmitter receptors available at a given time. In addition to the equilibrium between the biosynthetic production, exocytic delivery and recycling of receptors on the one hand, and the endocytic ...
Francisco J Barrantes
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Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis. [PDF]
, 2017 Natural-killer receptor group 2, member D (NKG2D) is a well characterized natural killer (NK) cell activating receptor that recognizes several ligands poorly expressed on healthy cells but up-regulated upon stressing stimuli in the context of cancer or ...
Molfetta, R +3 more
core +2 more sources
New immunolatex spheres: visual markers of antigens on lymphocytes for scanning electron microscopy [PDF]
, 1975 New immunochemical reagents consisting of antibodies bound to small latex spheres were used as visual markers for the detection and localization of cell surface antigens by scanning electron microscopy.
Dreyer, William J. +3 more
core +2 more sources
Molecular recognition of paired receptors in the immune system
Frontiers in Microbiology, 2012 Cell surface receptors are responsible for regulating cellular function on the front line, the cell membrane. Interestingly, accumulating evidence clearly reveals that the members of cell surface receptor families have very similar extracellular ligand ...
Kimiko eKuroki +4 more
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Phenotyping renal leukocyte subsets by four-color flow cytometry: Characterization of chemokine receptor expression [PDF]
, 2003 To investigate mechanisms of cell-mediated injury in renal inflammatory disease it is critical to determine the surface phenotype of infiltrating renal leukocyte subsets.
Anders, Hans-Joachim +5 more
core +1 more source
Selective inhibition of T suppressor-cell function by a monosaccharide [PDF]
, 1981 Interactions between regulatory T lymphocytes and other cells are assumed to occur at the level of the cell surface. T cells which suppress the generation of specifically effector cells have been described as having antigenic, idiotypic, allotypic and I ...
AA Moscona +22 more
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Anterograde Trafficking of CXCR4 and CCR2 Receptors in a Prostate Cancer Cell Line
Cellular Physiology and Biochemistry, 2013 Background: Most prostate cancer-related deaths result from metastasis. CXCR4 and CCR2 are known to govern cellular processes resulting in cell migration, proliferation and survival.
Kelsie Gillies +3 more
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Frontiers in Cell and Developmental Biology, 2021 Tumor necrosis factor-associated ligand inducing apoptosis (TRAIL) induces apoptosis through the death receptors (DRs) 4 and 5 expressed on the cell surface. Upon ligand stimulation, death receptors are rapidly internalized through clathrin-dependent and
Artem A. Artykov +8 more
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