Results 21 to 30 of about 1,161,650 (208)

Topological and Structural Plasticity of the Single Ig Fold and the Double Ig Fold Present in CD19

open access: yesBiomolecules, 2021
The Ig fold has had a remarkable success in vertebrate evolution, with a presence in over 2% of human genes. The Ig fold is not just the elementary structural domain of antibodies and TCRs, it is also at the heart of a staggering 30% of immunologic cell ...
Philippe Youkharibache
doaj   +1 more source

Cell-surface translational dynamics of nicotinic acetylcholine receptors

open access: yesFrontiers in Synaptic Neuroscience, 2014
Synapse efficacy heavily relies on the number of neurotransmitter receptors available at a given time. In addition to the equilibrium between the biosynthetic production, exocytic delivery and recycling of receptors on the one hand, and the endocytic ...
Francisco J Barrantes
doaj   +1 more source

Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis. [PDF]

open access: yes, 2017
Natural-killer receptor group 2, member D (NKG2D) is a well characterized natural killer (NK) cell activating receptor that recognizes several ligands poorly expressed on healthy cells but up-regulated upon stressing stimuli in the context of cancer or ...
Molfetta, R   +3 more
core   +2 more sources

New immunolatex spheres: visual markers of antigens on lymphocytes for scanning electron microscopy [PDF]

open access: yes, 1975
New immunochemical reagents consisting of antibodies bound to small latex spheres were used as visual markers for the detection and localization of cell surface antigens by scanning electron microscopy.
Dreyer, William J.   +3 more
core   +2 more sources

Molecular recognition of paired receptors in the immune system

open access: yesFrontiers in Microbiology, 2012
Cell surface receptors are responsible for regulating cellular function on the front line, the cell membrane. Interestingly, accumulating evidence clearly reveals that the members of cell surface receptor families have very similar extracellular ligand ...
Kimiko eKuroki   +4 more
doaj   +1 more source

Anterograde Trafficking of CXCR4 and CCR2 Receptors in a Prostate Cancer Cell Line

open access: yesCellular Physiology and Biochemistry, 2013
Background: Most prostate cancer-related deaths result from metastasis. CXCR4 and CCR2 are known to govern cellular processes resulting in cell migration, proliferation and survival.
Kelsie Gillies   +3 more
doaj   +1 more source

Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL

open access: yesFrontiers in Cell and Developmental Biology, 2021
Tumor necrosis factor-associated ligand inducing apoptosis (TRAIL) induces apoptosis through the death receptors (DRs) 4 and 5 expressed on the cell surface. Upon ligand stimulation, death receptors are rapidly internalized through clathrin-dependent and
Artem A. Artykov   +8 more
doaj   +1 more source

The trafficking and targeting of P2X receptors [PDF]

open access: yes, 2013
The functional expression of P2X receptors at the plasma membrane is dependent on their trafficking along secretory and endocytic pathways. There are seven P2X receptor subunits, and these differ in their subcellular distributions because they have very ...
Murrell-Lagnado, Ruth D   +1 more
core   +3 more sources

Interaction of KSHV with Host Cell Surface Receptors and Cell Entry

open access: yesViruses, 2014
Virus entry is a complex process characterized by a sequence of events. Since the discovery of KSHV in 1994, tremendous progress has been made in our understanding of KSHV entry into its in vitro target cells.
Mohanan Valiya Veettil   +3 more
doaj   +1 more source

Immunosuppressive Property of MSCs Mediated by Cell Surface Receptors

open access: yesFrontiers in Immunology, 2020
In the past decade, mesenchymal stem cells (MSCs) tend to exhibit inherent tropism for refractory inflammatory diseases and engineered MSCs have appeared on the market as therapeutic agents.
Siyu Liu   +5 more
doaj   +1 more source

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