Results 1 to 10 of about 99,477 (119)

Measles virus glycoprotein-based lentiviral targeting vectors that avoid neutralizing antibodies [PDF]

, 2012
Lentiviral vectors (LVs) are potent gene transfer vehicles frequently applied in research and recently also in clinical trials. Retargeting LV entry to cell types of interest is a key issue to improve gene transfer safety and efficacy.
Abel, Tobias, Brynza, Julia, Buchholz, Christian J., Kneissl, Sabrina, Rasbach, Anke, Schneider-Schaulies, Jürgen   +5 more
core   +15 more sources

Hepatitis B Virus Infection Among Leprosy Patients: A Case for Polymorphisms Compromising Activation of the Lectin Pathway and Complement Receptors

Frontiers in Immunology, 2021
Thousands of leprosy patients not only suffer from physical deformities, but also either have or have had hepatitis B virus (HBV) coinfection. Polymorphisms of the complement system modulate susceptibility to leprosy, but genetic susceptibility to past ...
Angelica Beate Winter Boldt, Angelica Beate Winter Boldt, Camila de Freitas Oliveira-Toré, Gabriela Canalli Kretzschmar, Hellen Weinschutz Mendes, Sérvio Túlio Stinghen, Fabiana Antunes Andrade, Valéria Bumiller-Bini, Letícia Boslooper Gonçalves, Anna Carolina de Moraes Braga, Ewalda von Rosen Seeling Stahlke, Thirumalaisamy P. Velavan, Thirumalaisamy P. Velavan, Thirumalaisamy P. Velavan, Steffen Thiel, Iara José Taborda de Messias-Reason   +15 more
doaj   +1 more source

Expression of genes encoding non-specific immunity, anti-oxidative status and aquaporins in β-glucan-fed golden mahseer (Tor putitora) juveniles under ammonia stress

Fish and Shellfish Immunology Reports, 2023
The study investigated the effects of dietary administration of β-glucan on aquaporins and antioxidative & immune gene expression in endangered golden mahseer, Tor putitora juveniles, exposed to ammonia stress.
Alexander Ciji, Priyanka H. Tripathi, Anupam Pandey, Md Shahbaz Akhtar   +3 more
doaj   +1 more source

Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. [PDF]

, 2018
Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and cancer. While p53 activation is responsible for many features of DBA, the role of immune system is less defined.
Bibikova, Elena, Danilova, Nadia, Lin, Shuo, Sakamoto, Kathleen M, Wilkes, Mark, Youn, Min-Young   +5 more
core   +2 more sources

Estrogens regulate neuroinflammatory genes via estrogen receptors α and β in the frontal cortex of middle-aged female rats

Journal of Neuroinflammation, 2011
Background Estrogens exert anti-inflammatory and neuroprotective effects in the brain mainly via estrogen receptors α (ERα) and β (ERβ). These receptors are members of the nuclear receptor superfamily of ligand-dependent transcription factors. This study
Mahó Sándor, Széles János, Tóth Kinga, Likó István, Solymosi Norbert, Kalló Imre, Hrabovszky Erik, Sárvári Miklós, Molnár Béla, Liposits Zsolt   +9 more
doaj   +1 more source

Peripheral inflammation is associated with remote global gene expression changes in the brain [PDF]

, 2014
Background: Although the central nervous system (CNS) was once considered an immunologically privileged site, in recent years it has become increasingly evident that cross talk between the immune system and the CNS does occur. As a result, patients with
Cavanagh, Jonathan, Graham, Gerard J., McColl, Alison, Thomson, Carolyn A.   +3 more
core   +2 more sources

Synapse elimination and learning rules co-regulated by MHC class I H2-Db. [PDF]

, 2014
The formation of precise connections between retina and lateral geniculate nucleus (LGN) involves the activity-dependent elimination of some synapses, with strengthening and retention of others. Here we show that the major histocompatibility complex (MHC)
Adelson, Jaimie, Brott, Barbara, Cheng, Sarah, Datwani, Akash, Feller, Marla, Kirkby, Lowry, Lee, Hanmi, Shatz, Carla   +7 more
core   +3 more sources

Zika virus infection reprograms global transcription of host cells to allow sustained infection. [PDF]

, 2017
Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenital microcephaly and Guillain-Barré syndrome. There are currently no targeted therapies for ZIKV infection.
Bansal, Vikas, Dang, Jason, Lichinchi, Gianluigi, Qin, Yue, Rana, Tariq M, Tiwari, Shashi Kant   +5 more
core   +2 more sources

MRI Tracking of Macrophages Labeled with Glucan Particles Entrapping a Water Insoluble Paramagnetic Gd-Based Agent. [PDF]

, 2012
PURPOSE: This study is aimed at demonstrating the in vivo potential of Gd(III)-loaded glucan particles (Gd-GPs) as magnetic resonance imaging (MRI)-positive agents for labeling and tracking phagocytic cells.
Aime, Silvio, Cutrin, Juan Carlos, De Luca, Elisa, Figueiredo, Sara, Geraldes, Carlos FGC, Moreira, Juao Nuno, Rizzitelli, Silvia, Terreno, Enzo   +7 more
core   +1 more source

Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? [PDF]

, 2016
Indexación: Web of Science.Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T.
A Colombo, A Morello, A Morillo, Arturo Ferreira, B Berwin, C Junqueira, C Ribeiro, C Valck, Carlos González, Carlos Rosas, E Sosoniuk, FJ Sánchez, FJ Sánchez, G Ramirez, G Ramírez, G Ramírez, Galia Ramírez, H Adachi, Ismael Maldonado, J Canton, J Clayton, Javier Pizarro-Bauerle, JC Aguillon, JC Aguillon, JD Maya, Jorge Ferreira, K Ahn, L Aguilar, L Aguilar, L Ubillos, Lorena Aguilar-Guzmán, M Michalak, M Obeid, M Pavani, MF Festing, NC López, Paula Abello-Cáceres, R Ramos, RH Berg Van den, V Ferreira, V Toledo, VD Kallinikova, Z Batmonkh   +42 more
core   +1 more source