Results 101 to 110 of about 88,745 (191)
CLDN18.2 CAR‐T cell‐derived small extracellular vesicles (CAR‐sEVs) display potent cytotoxicity and prolong survival in preclinical pancreatic cancer models. They contain functional CAR proteins and granzyme B, exhibit antigen specificity, and effectively target tumor cells while sparing healthy cells.
Yue Qing+7 more
wiley +1 more source
Light‐Activatable Hyaluronic Acid‐Derivatives Releasing Nitric Oxide and Their Delivery in the Skin
This work explores the development of photoactivatable hyaluronic acid (HA) derivatives functionalized with nitric oxide (NO) photodonors for light‐controlled therapeutic applications. The HA derivatives demonstrate enhanced keratinocyte proliferation and migration, effective NO release, and skin penetration when formulated as microemulsions.
Giuseppe Longobardi+7 more
wiley +1 more source
Through tuning biomimetic scaffold stiffness and matrix composition the reparative capacity of astrocyte progenitors is enhanced. Soft, collagen‐IV/fibronectin‐functionalized scaffolds promote progenitor growth while improving angiogenic, immunomodulatory, and neurotrophic capacity in a stiffness and matrix‐dependent manner, demonstrating the impact of
Cian O'Connor+10 more
wiley +1 more source
Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum+28 more
wiley +1 more source
Optoelectronic Devices for In‐Sensor Computing
The raw data obtained directly from sensors in the noisy analogue domain is often unstructured, which lacks a predefined format or organization and does not conform to a specific data model. Optoelectronic devices for in‐sensor visual processing can integrate perception, memory, and processing functions in the same physical units, which can compress ...
Qinqi Ren+7 more
wiley +1 more source
Mastering Proton Activities in Aqueous Batteries
Advanced aqueous batteries are promising alternatives for grid energy storage. Understanding and mastering the proton activities in aqueous electrolytes will guide the design of sustainable and long‐lasting aqueous batteries. This Perspective comments on the current understanding of the thermodynamic and kinetic perspectives of proton activities and ...
Leiting Zhang, Chao Zhang, Erik J. Berg
wiley +1 more source
The outstanding double‐cable‐based single‐component material, DCPY2, exhibits a suppressed charge recombination process alongside efficient charge generation. This results in a high fill factor and short‐circuit current, yielding an efficiency to 13.85%.
Yao Li+19 more
wiley +1 more source
A Bio‐Inspired Perspective on Materials Sustainability
This perspective discusses natural materials as inspiration for sustainable engineering designs and the processing of materials. First, circularity, longevity, parsimony, and activity are presented as essential material paradigms. The perspective then uses many examples of natural and technical materials to introduce principles such as oligo ...
Wolfgang Wagermaier+2 more
wiley +1 more source
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li+3 more
wiley +1 more source
Retrospective Review on Reticular Materials: Facts and Figures Over the Last 30 Years
To shape the future course of research in reticular materials, this work reflects on the progress over the past 30 years, complemented by input from the community of 228 active researchers through a global, crowdsourced survey: ranging from demographics, how it works, publish and interact, to highlights on both academic and industrial milestones, as ...
Aamod V. Desai+8 more
wiley +1 more source