Results 1 to 10 of about 563,405 (253)

Fish FSH receptors bind LH: How to make the human FSH receptor to be more fishy?

General and Comparative Endocrinology, 2005
In mammals, the interactions between glycoprotein hormones and their cognate receptors are highly specific; unintended cross-reactivity under normal physiological conditions has not been observed. The interactions between fish gonadotropins and their receptors, on the other hand, appeared to be less discriminatory.
Bogerd, J., Granneman, J.C.M., Schulz, R.W., Vischer, H.F.   +3 more
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Primate FSH-receptor promoter nucleotide sequence heterogeneity affects FSH-receptor transcription

Molecular and Cellular Endocrinology, 2010
Follicle-stimulating hormone (FSH) is essential for primate reproduction and acts via the FSH-receptor (FSHR). Although the FSHR expression is highly cell-specific, knowledge of the FSHR promoter and its transcriptional regulation is very limited. We applied a comparative genomic approach of important primate lineages to characterize the FSHR core ...
Maik, Brune, Christian, Adams, Jörg, Gromoll   +2 more
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FSH receptors in the bovine corpus luteum

Theriogenology, 1984
Binding of follicle stimulating hormone (FSH) to a crude membrane fraction of bovine corpus luteum (CL) has been detected. This binding meets the usual criteria for a receptor based on specificity, time course of reaction and association constant (Ka = 8.5 x 10(10)M(-1)). Physiological studies with CL removed from heifers at specific times after estrus
J G, Manns, G D, Niswender, T, Braden
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Genetic complexity of FSH receptor function

Trends in Endocrinology & Metabolism, 2005
The interaction between follicle-stimulating hormone (FSH) and the FSH receptor (FSHR) is essential for normal oogenesis and spermatogenesis. Recently, single-nucleotide polymorphisms (SNPs) have been assigned to the FSHR gene. These give rise to different FSHR haplotypes that modify the action of FSH.
GROMOLL J, SIMONI, Manuela
openaire   +2 more sources

Expression of FSH and its co-localization with FSH receptor and GnRH receptor in rat cerebellar cortex

Journal of Molecular Histology, 2012
The expression of follicle-stimulating hormone (FSH) and its receptor in extrapituitary and non-HPG axis tissues has been demonstrated and their non-reproductive functions in these tissues have been found. However, there have been no reports concerning the expression and function of FSH and its receptor in the cerebellum.
Chenyu, Chu, Jing'an, Zhou, Yaqun, Zhao, Ce, Liu, Pengfei, Chang, Qing, Zhou, Li, Zhao, Weiquan, Huang   +7 more
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Interaction of Follicle‐Stimulating Hormone (FSH) Receptor Binding Inhibitor‐8: A Novel FSH‐Binding Inhibitor, with FSH and its Receptor

Chemical Biology & Drug Design, 2009
Follicle‐stimulating hormone (FSH) receptor binding inhibitor (FRBI‐8) is a novel octapeptide purified from human ovarian follicular fluid. In vitro, it inhibits the binding of FSH to granulosa cells and in vivo, it induces atresia in developing follicles in rodents.
Swati S, Chitnis, Chellasamy, Selvaakumar, Dhanashree D, Jagtap, Ravi P, Barnwal, Kandala V R, Chary, Smita D, Mahale, Tarala D, Nandedkar   +6 more
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Two receptor binding regions of human FSH show sense-antisense similarity to the human FSH receptor

Biochemical and Biophysical Research Communications, 1991
The sequences of two receptor binding regions of the beta-subunit of the human follicle-stimulating hormone (hFSH-beta) were compared with the DNA-derived antisense peptide sequence of the hFSH receptor. A striking sense-antisense similarity was established between these receptor binding regions and the hFSH receptor.
J W, Slootstra, E W, Roubos
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Regulation of Expression of the FSH Receptor

1993
Follicle stimulating hormone (follitropin [FSH]) is a pituitary glycoprotein hormone that is essential for normal reproduction in both male and female mammals. Sertoli cells and granulosa cells are the target cells for the action of FSH in the testes and ovaries, respectively.
Michael D. Griswold, Leslie L. Heckert
openaire   +1 more source

Functional and clinical consequences of mutations in the FSH receptor

Molecular and Cellular Endocrinology, 1996
The follicle-stimulating hormone (FSH) is essential for normal gametogenesis. In females FSH is required for ovarian development and follicle maturation whereas in males FSH determines Sertoli cell number and quantitatively and qualitatively normal spermatogenesis. FSH action is mediated by a G-protein coupled receptor expressed solely in granulosa and
J, Gromoll, M, Simoni, V, Nordhoff, H M, Behre, C, De Geyter, E, Nieschlag   +5 more
openaire   +2 more sources

Studies on the mechanism of LH receptor control by FSH

Molecular and Cellular Endocrinology, 1982
Abstract The mechanism of the control of LH/hCG receptor by FSH was investigated using granulosa cells from the immature hypophysectomized estrogen primed rat as a model. The specific binding of [ 125 I]hCG to freshly collected granulosa cells was low (0.18 ± 0.01 fmoles/10 6 cells). By contrast, a marked increase in [ 125 I]hCG binding was observed
G F, Erickson, C, Wang, R, Casper, G, Mattson, C, Hofeditz   +4 more
openaire   +2 more sources