Results 101 to 110 of about 23,039 (305)

Follicle-Stimulating Hormone Receptors in Oocytes?

, 2002
International audienceThe regulatory mechanisms of oocyte maturation remain poorly understood. Although gonadotropins play a major role in these processes, they have generally been considered to act on somatic supportive cells, but not directly on germ ...
Milgrom, Edwin, Meduri, Geri, Combettes, Laurent, Granet, Philippe, Vannier, Brigitte, Loosfelt, Hugues, Charnaux, Nathalie, Driancourt, Marc-Antoine   +7 more
core   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

Environmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida, Thalita Tofanin Sargiani D'Assumpção, Ana Priscila Gomes Silva, Carolina Rocha Moreira de Oliveira, Tailisi Hoppe Trevizani, Rubens Cesar Lopes Figueira, Lucas Buruaem Moreira, Juliana Elaine Perobelli   +7 more
wiley   +1 more source

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Controlled Study of Women After Pre‐Menopausal Risk‐Reducing Bilateral Salpingo‐Oophorectomy

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Surgical menopause, the removal of both ovaries prior to natural menopause, may impact short‐and long‐term physical and emotional health. An increasingly common cause of surgical menopause is risk‐reducing salpingo‐oophorectomy (RRSO) in those at high inherited risk of ovarian cancer.
Sarah A. L. Price, Pauline M. Maki, Samar R. El Khoudary, Alison Brand, Rakibul M. Islam, Susan M. Domchek, Hadine Joffe, Gita D. Mishra, Katrina M. Moss, Fiona C. Baker, Sabine Braat, John D. Wark, Martha Hickey   +12 more
wiley   +1 more source

Gonadotropins in Keratoconus: The Unexpected Suspects

Cells, 2019
Keratoconus (KC) is the most common ectatic corneal disease with a significant visual acuity burden. The actual burden is intangible given that KC can disrupt daily activities (reading, driving, and various career paths).
Dimitrios Karamichos, Brayden Barrientez, Sarah Nicholas, Symon Ma, Lyly Van, Sashia Bak-Nielsen, Jesper Hjortdal   +6 more
doaj   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Follicle-stimulating hormone peptide-conjugated nanoparticles for targeted shRNA delivery lead to effective gro-α silencing and antitumor activity against ovarian cancer

Drug Delivery, 2018
The distinct hormone molecules and receptors, such as follicle-stimulating hormone receptor (FSHR) in ovarian cancer, provide opportunities for more precisely targeted therapy.
Shan-Shan Hong, Ming-Xing Zhang, Meng Zhang, Yi Yu, Jun Chen, Xiao-Yan Zhang, Cong-Jian Xu   +6 more
doaj   +1 more source

Comparative Effects of Clinical Pilates Training and Aerobic Exercise on Menopausal Symptoms, Quality of Life, Sleep and Depression: A Randomised Controlled Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine the effects of Clinical Pilates (CP) training and aerobic exercise (AE) on menopausal symptoms, depressive symptoms, quality of life (QoL), and sleep quality in postmenopausal women. Design Parallel‐group randomised controlled trial. Setting A Healthy Life Center in Bitlis, Turkey.
Başak Can, Serkan Usgu, Günseli Usgu
wiley   +1 more source

An activated human follicle-stimulating hormone (FSH) receptor stimulates FSH-like activity in gonadotropin-deficient transgenic mice

, 2002
FSH mediates its testicular actions via a specific Sertoli cell G protein-coupled receptor. We created a novel transgenic model to investigate a mutant human FSH receptor (FSHR(+)) containing a single amino acid substitution (Asp567Gly) equivalent to ...
HAYWOOD M, ALLAN CM, GROMOLL J, SPALIVERO J, HANDELSMAN DJ, TYMCHENKO N, NORDHOFF V, KOCH A, JIMENEZ M, M. SIMONI   +9 more
core   +1 more source

Microbial and Metabolic Correlates of Endometrial Dysfunction in Polycystic Ovary Syndrome: A Translational Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Women with polycystic ovary syndrome (PCOS) exhibit a substantially increased risk of miscarriage, yet the underlying mechanisms remain inadequately understood. This study aimed to investigate whether specific gut microbial dysbiosis and metabolic disturbance are associated with and may potentially contribute to endometrial ...
Mengyu Jing, Xi Chen, Meiyan Jiang, Huiya Fang, Xiaoming Zhu, Xuejing Jin, Yonghui Jiao, Ningning Hou, Weiwei Gong, Aixia Liu   +9 more
wiley   +1 more source

Effect of Salinity Stress on Gut–Brain–Gonad Axis in the Red‐Eared Slider (Trachemys scripta elegans)

Integrative Zoology, EarlyView.
The increase in salinity leads to changes in the gut microbiota and metabolites of Trachemys scripta elegans, affecting the synthesis and secretion of neurotransmitters or precursors, which can inhibit the secretion of reproductive hormones and affect the self‐renewal and differentiation process of spermatogonial stem cells.
Qiongyu Zhang, Na Li, Xue Tang, Hanru Chen, Meiling Hong, Li Ding   +5 more
wiley   +1 more source