Results 171 to 180 of about 563,405 (253)

G protein coupled receptors.

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation ...
Conn, P. Michael.
core  

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

From Association to Mechanism: Regulatory Annotation and Pathway Mapping of Genes Surrounding Breast Cancer Risk Variants

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Inherited factors account for a large share of breast cancer susceptibility, yet the biological consequences of most risk variants are still poorly understood. To address this gap, we studied 175 breast cancer risk variants confirmed by genome‐wide association studies and gathered the genes that lie near them.
Sultana Jannat, Trina Mitra, Nafisa Nawar Fariha, Tasmia Tabassum, Kulsuma Bahar Bethi, Synchita Majumder Kaya, Md. Arif Hossen, Md. Saad Hossain, Jobaier Ibne Deen, Mohammed Emon, Laila Khaleda, Md. Hridoy Ahmed   +11 more
wiley   +1 more source

ManyBabies 3: A Multi‐Lab Study of Infant Algebraic Rule Learning

Developmental Science, Volume 29, Issue 6, November 2026.
ABSTRACT The ability to learn and apply rules lies at the heart of cognition. In a seminal study, Marcus et al. (1999) reported that 7‐month‐old infants learned abstract rules over syllable sequences and were able to generalize those rules to novel syllable sequences.
Ingmar Visser, Andreea Geambasu, George Kachergis, Cátia M. Oliveira, Joscelin Rocha‐Hidalgo, Martin Zettersten, Teruni Ahamat, Nicolás Alessandroni, Nadja Althaus, Sudha Arunachalam, Suzanne Aussems, Emma L Axelsson, Zeynep Aydin, Heidi A. Baumgartner, Christina Bergmann, Roberta Bettoni, Alexis K. Black, Hermann Bulf, Krista Byers‐Heinlein, Chiara Capparini, Lily Carroll, Alexandra Carstensen, Rebekka Cebulla, Xiaoyun Chen, Kateřina Chládková, Benedetta Colavolpe, Rodica R Constantine, Elísabet Eir Cortes, Frances L. Doyle, Anna Exner, Samuel H Forbes, Laura Franchin, Alessandra Geraci, Judit Gervain, Nayeli Gonzalez‐Gomez, Silje Hagelund, Erin E Hannon, Naomi Havron, Sagi Jaffe‐Dax, Scott P Johnson, Wiktoria Jędryczka, Natalia Kartushina, Melissa Kline Struhl, Ada Koleini, Abhinav Kona, Shannon P Kong, Jessica E Kosie, Monika Kuc̆erová, Katerina Cook, Jared Wayne Leslie, Casey Lew‐Williams, Scarlet Wan Yee Li, Romi Livne, Ellen Marklund, Julien Mayor, Michal Misiak, David Moreau, Jutta L. Mueller, Amber Muhinyi, Alyssa A Quinn, Maartje E. J. Raijmakers, Audun Rosslund, Iris‐Corinna Schwarz, Jeanne L Shinskey, Mohinish Shukla, Sylvain Sirois, Piotr Sorokowski, Basma Sowan, Tibor Tauzin, Angeline Sin Mei Tsui, Martina Turconi, Rebeca C Urizar, Lisa Wagner, Stephanie Wermelinger, Gert Westermann, Ivonne Weyers, Luiza S. B. Yuan, Martina S. Zaharieva, Tania S. Zamuner, Barbara Zapiór, Simone Zasso, J. Grace Zhou, Melanie Soderstrom, Clara C. Levelt   +83 more
wiley   +1 more source

A Wagner–Meerwein‐Like Rearrangement Generates a Vinyl Group in the Biosynthesis of the Polychlorinated Lipopeptides Fischerazoles

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
The fischerazoles, unusual cyanobacterial chlorinated lipopeptides are reported. During their biosynthesis, a linear fatty acyl‐acyl carrier protein (ACP) precursor is rearranged through the action of the S‐adenosyl‐methionine (SAM)‐dependent methyltransferase FshF, to generate a pendant vinyl group.
Sandra A. C. Figueiredo, Kathleen Abt, Konrad Viehrig, Peter J. Jervis, Teresa P. Martins, Iñaki Lacomba, Chuhan Li, Daniele Castagnolo, Pedro N. Leão   +8 more
wiley   +2 more sources

Preclinical and Toxicology Studies of LPM7100328, a Novel Oral GnRH Antagonist

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in favor of human clinical trials.
Yao Wang, Junxian Zhao, Fangxia Zou, Wanglin Jiang, Jianzhao Zhang, Pengfei Yu, Liang Ye, Xiaolin Sun, Chunmei Li, Jingwei Tian   +9 more
wiley   +1 more source

Effects of Trazodone on Testicular Morphology, Sperm Parameters and Contractility of the Distal Cauda Epididymal Duct in Rats

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Trazodone is an antidepressant approved for the treatment of major depressive disorder and is associated with a low incidence of sexual dysfunction. However, its effects on male reproductive health are not yet fully understood. Therefore, this study aimed to evaluate the effects of repeated trazodone administration on reproductive parameters ...
Maria Santana da Silva, Vitória Barros Marques, Fernanda Karoline Oliveira da Silva, Maele Oliveira de Sena, Yanka do Vale Carvalho, Bruna da Silva Figueiredo, Luana Talinne da Costa Gomes, Samia Ellen Alves Fernandes, Edherlayne Bezerra dos Santos Silva, Jackson Nazareno Gomes de Lima, Anna Karynna Alves de Alencar Rocha, Expedito Silva do Nascimento Junior, Elaine Cristina Gavioli, Edilson Dantas da Silva Junior   +13 more
wiley   +1 more source

Hypogonadotropic Hypogonadism Before and After Transsphenoidal Surgery for Non‐Functioning Pituitary Adenoma

Clinical Endocrinology, Volume 105, Issue 4, Page 442-451, October 2026.
ABSTRACT Objective The effect of transsphenoidal surgery (TSS) on the hypothalamic‐pituitary‐gonadal (HPG) axis in patients with non‐functioning pituitary adenomas (NFPA) is underexplored, especially in women. Our aim was to investigate the HPG axis function before and after TSS, its association with quality of life (QoL), and to identify factors that ...
Victor Hantelius, Gudmundur Johannsson, Sofie Jakobsson, Erik Thurin, Tobias Hallen, Thomas Skoglund, Oskar Ragnarsson   +6 more
wiley   +1 more source

The Spectrum of Congenital Hypogonadotropic Hypogonadism: A 30‐Year Experience at a Tertiary Paediatric Centre

Clinical Endocrinology, Volume 105, Issue 4, Page 464-473, October 2026.
ABSTRACT Congenital hypogonadotropic hypogonadism (CHH) is a rare group of disorders of gonadotropin deficiency, either isolated or as a part of multiple pituitary hormone deficiencies (MPHD). We aimed to describe the spectrum of presentation, diagnosis, and management practices of CHH spanning 30 years at an Australian tertiary paediatric centre. This
Minha Kook, Richard G. McGee, Geoffrey Ambler, Yoon Hi Cho   +3 more
wiley   +1 more source

Soluble FSH receptors from the rat testis

FEBS Letters, 1977
Dufau, Maria L., Ryan, David W., Catt, Kevin J.   +2 more
openaire   +2 more sources