Results 211 to 220 of about 23,039 (305)

Polymorphism of the <i>FSHB</i> Gene Is Associated with Endometrial Hyperplasia. [PDF]

open access: yesLife (Basel)
Churnosov V   +9 more
europepmc   +1 more source

Electrical Impedance Myography Detects Disease Progression over 12 to 24 Months in Facioscapulohumeral Muscular Dystrophy

open access: yesAnnals of Neurology, Volume 99, Issue 6, Page 1545-1554, June 2026.
Objective Targeted therapies for facioscapulohumeral muscular dystrophy (FSHD) are progressing through clinical trials. Electrical impedance myography (EIM) provides a noninvasive biomarker of muscle composition that may be valuable especially in early phase trials. This study evaluated EIM data from a multicenter FSHD cohort over 24 months.
Karlien Mul   +68 more
wiley   +1 more source

Bioequivalence of a Fixed‐Dose Combination of Relugolix, Estradiol, and Norethindrone Acetate: An Open‐Label, Randomized, Fully Replicate Crossover Study in Healthy Postmenopausal Women Under Fasting Conditions

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 6, June 2026.
Abstract Uterine fibroids are the most common benign gynecological tumors, often causing heavy menstrual bleeding (HMB), anemia, and impaired quality of life. A fixed‐dose combination (FDC) of relugolix (40 mg), estradiol (1 mg), and norethindrone acetate (0.5 mg) was developed to address these limitations.
Ravi Kotadia   +6 more
wiley   +1 more source

Lactate metabolism and lactylation in female reproductive diseases: From metabolic rewiring to biomarkers and translational therapeutics

open access: yesClinical and Translational Medicine, Volume 16, Issue 6, June 2026.
1. Lactate‐derived histone lactylation links glycolytic reprogramming to epigenetic regulation in female reproductive diseases. 2. In endometriosis, lactylation may promote inflammatory remodelling, immune dysregulation and ferroptosis resistance. 3. In PCOS, lactylation connects metabolic disturbance to granulosa‐cell dysfunction and hyperandrogenism.
Jiajun Qiao   +5 more
wiley   +1 more source

Advances in the Use of Recombinant Gonadotropins for Reproductive Biotechnologies in Ruminants: A Review. [PDF]

open access: yesReprod Domest Anim
Di Domenico VL   +5 more
europepmc   +1 more source

Electroacupuncture Ameliorates Premature Ovarian Insufficiency by Inhibiting METTL3‐Mediated m6A Methylation of Beclin 1 mRNA in Granulosa Cells

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
A high‐fat, high‐sugar (HFHS) diet induces premature ovarian insufficiency (POI), characterized by reduced follicular reserve, increased atresia, fibrosis, and excessive granulosa cell autophagy. Electroacupuncture (EA) at CV4, ST36, and SP6 suppresses METTL3 expression and reduces m6A methylation of Beclin1 mRNA, thereby limiting Beclin1 translation ...
Lele Ling   +9 more
wiley   +1 more source

Pharmacological rescue of follicle-stimulating hormone receptor mutants. In vitro and in silico studies.

open access: yesEndocrinology
Zariñán T   +6 more
europepmc   +1 more source

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