Results 161 to 170 of about 618,319 (304)

Beyond Histamine: Mast Cell-Neuron Communication in Chronic Pruritic and Pain Disorders. [PDF]

Exp Dermatol
Kagan T, Yosipovitch G.
europepmc   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean‐Christoph Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

Kappa opioids suppress histaminergic itch by inhibiting mediodorsal thalamus-projecting claustrum glutamatergic neurons. [PDF]

Sci Adv
Liu Z, Shu X, Wang Z, Yao S, Hu C, Wang B, Liu P, Feng L, Shen Y, Xiao H, Liu JG, Wang YJ.   +11 more
europepmc   +1 more source

Factors for Success and Failure of Allergen Immunotherapy (AIT) Trial Design in the Light of Evidence‐Based Medicine: Current Aspects 2026

Allergy, EarlyView.
ABSTRACT Allergen immunotherapy (AIT) has been acknowledged as the only disease‐modifying treatment for respiratory diseases since its introduction in 1911. Although the efficacy and safety have convincingly been established in numerous randomized clinical trials (RCTs), the AIT study results may vary substantially.
Roy Gerth van Wijk, Vera Mahler, Melanie Albrecht, Danilo di Bona, Benjamin Hofner, Jasper Kappen, Susanne Kaul, Graham Roberts, Mohamed H. Shamji, Stefan Vieths, Oliver Pfaar   +10 more
wiley   +1 more source

Antipsychotics and Sleep Architecture: Where Does Lurasidone Fit? [PDF]

Cureus
Pham B, Siddiq S.
europepmc   +1 more source

Role of Cysteinyl Leukotrienes in Food Allergy and Anaphylaxis: A Potential Therapeutic Target

Allergy, EarlyView.
Adrienn Weingärtner, Thomas Eiwegger
wiley   +1 more source

Mepolizumab Modifies Blood Eosinophil Proteome and Transcriptome in Severe Eosinophilic Asthma

Allergy, EarlyView.
This study investigates the effect of mepolizumab on the proteomic and transcriptomic profile of blood eosinophils in SEA patients. Mepolizumab reduces the migratory capacity and effector‐related molecular signatures of circulating eosinophils in SEA patients.
Pablo Miguéns‐Suárez, Sara Vázquez‐Mera, Laura Martelo‐Vidal, Marina Blanco Aparicio, Uxío Calvo Álvarez, Coral González Fernández, Mar Mosteiro Añón, Dolores Corbacho Abelaira, Tamara Hermida Valverde, Christian Calvo Henríquez, Susana B. Bravo, Lena Uller, Juan J. Nieto‐Fontarigo, Francisco J. Salgado, Francisco J. González‐Barcala   +14 more
wiley   +1 more source

Vestibular disorders and monoamine neurotransmitters: Current evidence. [PDF]

iScience
Liu Y, Zhou L, Chen X, Tian E, Lu Y, Wu P, Zhang S, Wang J.   +7 more
europepmc   +1 more source

Failed Mucosal Allostasis Distinguishes Murine IgG‐ From IgE‐Mediated Recurrent Severe Anaphylaxis

Allergy, EarlyView.
This study investigates IgE‐ and IgG‐mediated pathways in acute and recurrent anaphylaxis using a murine ASA‐PSA model, assessing barrier integrity, immune activation and tissue remodelling across pulmonary and intestinal compartments. Recurrent IgE‐ and IgG‐mediated anaphylaxis produces divergent mucosal outcomes despite comparable systemic severity ...
Abdurrahman Simsek, Muhammed Ali Kizmaz, Tugce Bozkurt, Sude Toprakkaz, Mehmet Emre Topcu, Musa Ozgur Ozyigit, Ahmet Akkoc, Dane Ediger, Ferah Budak Sener   +8 more
wiley   +1 more source

Plant-Derived Diamine Oxidase Modulation of Histamine-Induced Ca²⁺ Release in Intestinal Caco-2 Cells: A Cellular System to Evaluate Its Histaminase Efficacy. [PDF]

Cells
Neree AT, Jumarie C, Marcocci L, Pietrangeli P, Mateescu MA.   +4 more
europepmc   +1 more source