Results 11 to 20 of about 41,179 (270)

Histamine H3 Heteroreceptors Suppress Glutamatergic and GABAergic Synaptic Transmission in the Rat Insular Cortex

Frontiers in Neural Circuits, 2017
Histamine H3 receptors are autoreceptors that regulate histamine release from histaminergic neuronal terminals. The cerebral cortex, including the insular cortex (IC), expresses abundant H3 receptors; however, the functions and mechanisms of H3 receptors
Hiroki Takei, Hiroki Takei, Kiyofumi Yamamoto, Kiyofumi Yamamoto, Yong-Chul Bae, Tetsuo Shirakawa, Masayuki Kobayashi, Masayuki Kobayashi, Masayuki Kobayashi   +8 more
doaj   +2 more sources

Plasticity of the histamine H3 receptors after acute vestibular lesion in the adult cat.

Frontiers in Integrative Neuroscience, 2014
After unilateral vestibular neurectomy (UVN) many molecular and neurochemical mechanisms underlie the neurophysiological reorganizations occurring in the vestibular nuclei (VN) complex, as well as the behavioral recovery process.
Brahim eTighilet, Christiane emourre, Michel eLacour   +2 more
doaj   +2 more sources

Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide imaging study in mice [PDF]

Molecular Brain
The histaminergic system plays a key role in modulating learning and memory, wakefulness, and energy balance. Histamine H3 receptors constitutively inhibit the synthesis and release of histamine and other neurotransmitters. Therefore, H3 receptor inverse
Sentaro Kaita, Yoshikazu Morishita, Kenta Kobayashi, Hiroshi Nomura   +3 more
doaj   +2 more sources

Carotid body plastic behavior: evidence for D2–H3 receptor–receptor interactions [PDF]

Frontiers in Physiology
Dopamine and histamine receptors D2R and H3R are G protein-coupled receptors (GPCRs) which can establish physical receptor–receptor interactions (RRIs), leading to homo/hetero-complexes in a dynamic equilibrium.
Elena Stocco, Elena Stocco, Elena Stocco, Aron Emmi, Maria Martina Sfriso, Aleksandar Tushevski, Raffaele De Caro, Veronica Macchi, Andrea Porzionato   +8 more
doaj   +2 more sources

Correlation of Histamine Receptors and Adrenergic Receptor in Broilers Appetite [PDF]

Archives of Razi Institute, 2022
The current study was conducted to investigate the interaction between the central adrenergic and histaminergic systems and the broiler chick’s feed intake.
M Daneshvar, M Zendehdel, B Vazir, A Asghari   +3 more
doaj   +1 more source

Histamine receptors in GtoPdb v.2023.1 [PDF]

, 2023
Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 174]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80].
Chazot, Paul, Cowart, Marlon, Fukui, Hiroyuki, Ganellin, C. Robin, Gutzmer, Ralf, Haas, Helmut L., Hill, Stephen J., Hills, Rebecca, Leurs, Rob, Levi, Roberto, Liu, Steve, Panula, Pertti, Schunack, Walter, Schwartz, Jean-Charles, Seifert, Roland, Shankley, Nigel P., Stark, Holger, Thurmond, Robin, Timmerman, Henk, Young, J. Michael   +19 more
core   +3 more sources

Histamine receptors in GtoPdb v.2021.3 [PDF]

, 2021
Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 173]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80]. The human and rat
Chazot, Paul, Cowart, Marlon, Fukui, Hiroyuki, Ganellin, C. Robin, Gutzmer, Ralf, Haas, Helmut L., Hill, Stephen J., Hills, Rebecca, Leurs, Rob, Levi, Roberto, Liu, Steve, Panula, Pertti, Schunack, Walter, Schwartz, Jean-Charles, Seifert, Roland, Shankley, Nigel P., Stark, Holger, Thurmond, Robin, Timmerman, Henk, Young, J. Michael   +19 more
core   +2 more sources

Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties

ACS Chemical Neuroscience, 2021
In an attempt to extend recent studies showing that some clinically evaluated histamine H3 receptor (H3R) antagonists possess nanomolar affinity at sigma-1 receptors (σ1R), we selected 20 representative structures among our previously reported H3R ...
K. Szczepańska, Sabina Podlewska, Maria Dichiara, Davide Gentile, Vincenzo Patamia, Niklas Rosier, Denise Mönnich, Ma Carmen Ruiz Cantero, T. Karcz, D. Łażewska, A. Siwek, Steffen Pockes, E. J. Cobos, A. Marrazzo, H. Stark, A. Rescifina, A. Bojarski, E. Amata, K. Kieć‐Kononowicz   +18 more
semanticscholar   +1 more source

Identification and characterization of ZEL-H16 as a novel agonist of the histamine H3 receptor. [PDF]

PLoS ONE, 2012
The histamine H3 receptor (H3R) has been recognized as a promising target for the treatment of various central and peripheral nervous system diseases.
Ying Shi, Rong Sheng, Tingting Zhong, Yu Xu, Xiaopan Chen, Dong Yang, Yi Sun, Fenyan Yang, Yongzhou Hu, Naiming Zhou   +9 more
doaj   +1 more source

UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H3 and H4 Receptors.

Journal of Medicinal Chemistry, 2020
Comprehensively characterized fluorescent probes for the histamine H3 receptor (H3R) and especially for the H4R orthologs [e.g., human (h) and mouse (m)] are highly needed as versatile complementary tools to radioligands.
Edith Bartole, Lukas Grätz, Timo Littmann, David Wifling, U. Seibel, A. Buschauer, G. Bernhardt   +6 more
semanticscholar   +1 more source