Results 31 to 40 of about 10,873 (200)

Histamine receptors in GtoPdb v.2023.1 [PDF]

, 2023
Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 174]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80].
Chazot, Paul, Cowart, Marlon, Fukui, Hiroyuki, Ganellin, C. Robin, Gutzmer, Ralf, Haas, Helmut L., Hill, Stephen J., Hills, Rebecca, Leurs, Rob, Levi, Roberto, Liu, Steve, Panula, Pertti, Schunack, Walter, Schwartz, Jean-Charles, Seifert, Roland, Shankley, Nigel P., Stark, Holger, Thurmond, Robin, Timmerman, Henk, Young, J. Michael   +19 more
core   +3 more sources

Histamine H3 Heteroreceptors Suppress Glutamatergic and GABAergic Synaptic Transmission in the Rat Insular Cortex

Frontiers in Neural Circuits, 2017
Histamine H3 receptors are autoreceptors that regulate histamine release from histaminergic neuronal terminals. The cerebral cortex, including the insular cortex (IC), expresses abundant H3 receptors; however, the functions and mechanisms of H3 receptors
Hiroki Takei, Hiroki Takei, Kiyofumi Yamamoto, Kiyofumi Yamamoto, Yong-Chul Bae, Tetsuo Shirakawa, Masayuki Kobayashi, Masayuki Kobayashi, Masayuki Kobayashi   +8 more
doaj   +1 more source

Time-Restricted Feeding Improves Circadian Dysfunction as well as Motor Symptoms in the Q175 Mouse Model of Huntington's Disease. [PDF]

, 2018
Huntington's disease (HD) patients suffer from a progressive neurodegeneration that results in cognitive, psychiatric, cardiovascular, and motor dysfunction.
Colwell, Christopher S, Cutler, Tamara, Howland, David, Loh, Dawn H, Wang, Huei-Bin, Whittaker, Daniel S   +5 more
core   +1 more source

Histamine receptors in GtoPdb v.2021.3 [PDF]

, 2021
Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 173]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80]. The human and rat
Chazot, Paul, Cowart, Marlon, Fukui, Hiroyuki, Ganellin, C. Robin, Gutzmer, Ralf, Haas, Helmut L., Hill, Stephen J., Hills, Rebecca, Leurs, Rob, Levi, Roberto, Liu, Steve, Panula, Pertti, Schunack, Walter, Schwartz, Jean-Charles, Seifert, Roland, Shankley, Nigel P., Stark, Holger, Thurmond, Robin, Timmerman, Henk, Young, J. Michael   +19 more
core   +2 more sources

Effects of methimepip and JNJ-5207852 in Wistar rats exposed to an open-field with and without object and in Balb/c mice exposed to a radial-arm maze [PDF]

, 2012
The role of the histamine H3 receptor (H3R) in anxiety is controversial, due to limitations in drug selectivity and limited validity of behavioral tests used in previous studies. In the present report, we describe two experiments.
Abuhamdah, Rushdie M., Chazot, Paul L., Ennaceur, Abdelkader, Lethbridge, Natasha L., van Rensburg, Ruan   +4 more
core   +1 more source

Low Brain Histamine Content Affects Ethanol-Induced Motor Impairment

Neurobiology of Disease, 2002
The effect of ethanol on motor performance in humans is well established but how neural mechanisms are affected by ethanol action remains largely unknown.
Minnamaija Lintunen, Kristiina Raatesalmi, Tina Sallmen, Oleg Anichtchik, Kaj Karlstedt, Jan Kaslin, Kalervo Kiianmaa, Esa R. Korpi, Pertti Panula   +8 more
doaj   +1 more source

Histamine H3 receptor density is negatively correlated with neural activity related to working memory in humans

EJNMMI Research, 2018
Background The histamine H3 receptor is regarded as a drug target for cognitive impairments in psychiatric disorders. H3 receptors are expressed in neocortical areas, including the prefrontal cortex, the key region of cognitive functions such as working ...
Takehito Ito, Yasuyuki Kimura, Chie Seki, Masanori Ichise, Keita Yokokawa, Kazunori Kawamura, Hidehiko Takahashi, Makoto Higuchi, Ming-Rong Zhang, Tetsuya Suhara, Makiko Yamada   +10 more
doaj   +1 more source

Histamine and its Effects Mediated via H3 Receptor – Potential Clinical Applications of H3 Antagonists

Acta Medica Martiniana, 2013
Histamine is one of the most important biogenic amines and it mediates numbers of physiological processes. It is also involved in majority of inflammatory diseases via its receptors H1, H2, H3 and H4.
Hanuskova E., Plevkova J.
doaj   +1 more source

Transient changes in the limbic histaminergic system after systemic kainic acid-induced seizures

Neurobiology of Disease, 2005
Increased brain histamine is reported to protect against convulsions. We used systemic kainic acid (KA) administration to study possible changes of the histaminergic system in rat brain in status epilepticus (SE).
Minnamaija Lintunen, Tina Sallmen, Kaj Karlstedt, Pertti Panula   +3 more
doaj   +1 more source

Heteroreceptor complexes formed by dopamine D1, histamine H3 and N-methyl-D-aspartate glutamate receptors as targets to prevent neuronal death in Alzheimer's disease [PDF]

, 2017
Alzheimer’s disease (AD) is a neurodegenerative disorder causing progressive memory loss and cognitive dysfunction. Anti-AD strategies targeting cell receptors consider them as isolated units. However, many cell surface receptors cooperate and physically
A Thathiah, AD Medhurst, AI Hersi, Antonio Cortés, C Ferrada, C Fiorentini, C Pillot, Carme Lluís, CG Mcnamara, D Wang, D Wilkinson, David Moreno-Delgado, DO Borroto-Escuela, DR Borchelt, DR Borchelt, E Moreno, E Moreno, Enric I. Canela, Estefanía Moreno, FJS Lee, G Navarro, G Navarro, G Navarro, G Navarro, Gemma Navarro, H Kaphzan, HJ Seong, IM Mazurkiewicz-Kwilecki, J Chen, J Wu, JD Brioni, Josefa Mallol, JY Koh, L Fernández-Novoa, M Wang, Mar Rodríguez-Ruiz, MB Passani, NP Sidharthan, P Giménez-Xavier, P Panula, Peter J. McCormick, PL Chazot, R Cacabelos, RA Grove, Rafael Franco, RF Cowburn, RJ Rodrigues, S Jürgensen, S-M Jeon, Vicent Casadó, WD Le   +50 more
core   +1 more source