Results 241 to 250 of about 1,113,949 (291)
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Expression of interleukin 2 and the interleukin 2 receptor in aging rats
Cellular Immunology, 1989Lymphocytes of aged animals exhibit a marked decrease in proliferative capacity in response to mitogen stimulation when compared to those of younger animals. In humans and mice the decreased proliferation is due at least in part (i) to the inability of lymphocytes to synthesize sufficient interleukin 2 (IL-2) and (ii) to decreased expression of IL-2 ...
Nikki J. Holbrook +6 more
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Soluble interleukin-2 receptors in systemic lupus erythematosus.
Arthritis & Rheumatism, 1988We studied levels of soluble interleukin-2 receptors (IL-2R), which are released by activated lymphocytes, in 139 serum samples from 12 patients with systemic lupus erythematosus (SLE).
Robert E. Wolf, William G. Brelsford
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Pathology, 1991
Following activation in vitro, peripheral blood mononuclear cells (PBMC) express cell-associated interleukin-2 receptors (IL2R). The present study was undertaken to define the proportion of T lymphocyte subsets that express the IL2R (CD25 antigen) upon different mitogenic stimulation.
Lai, FM, Leung, JCK, Lai, KN
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Following activation in vitro, peripheral blood mononuclear cells (PBMC) express cell-associated interleukin-2 receptors (IL2R). The present study was undertaken to define the proportion of T lymphocyte subsets that express the IL2R (CD25 antigen) upon different mitogenic stimulation.
Lai, FM, Leung, JCK, Lai, KN
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Prolactin induction of interleukin-2 receptors on rat splenic lymphocytes.
Endocrinology, 1990A case for the involvement of PRL in the regulation of the immune system is strong. However, no mechanism by which PRL exerts this regulation has yet been identified.
P. Mukherjee, A. Mastro, W. Hymer
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The Interleukin 2 Receptor in the Hypereosinophilic Syndrome
Leukemia & Lymphoma, 1992The hypereosinophilic syndrome (HES) has been previously described as a clinicobiological entity characterized by a blood eosinophil count of over 1.5 x 10(9)/L of unknown cause associated with several clinical complications. In reality, HES is a heterogeneous group of diseases with variable and unpredictable progress in visceral lesions, thought to be
Plumas, Joël +4 more
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1985
Interleukin-2 (IL-2) is a lymphokine synthesized by some T-cells following activation. Resting T-cells do not express IL-2 receptors but receptors are rapidly expressed on T-cells following the interaction of antigens, mitogens, or monoclonal antibodies with the antigen specific T-cell receptor complex.
Kathleen F. Bongiovanni +6 more
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Interleukin-2 (IL-2) is a lymphokine synthesized by some T-cells following activation. Resting T-cells do not express IL-2 receptors but receptors are rapidly expressed on T-cells following the interaction of antigens, mitogens, or monoclonal antibodies with the antigen specific T-cell receptor complex.
Kathleen F. Bongiovanni +6 more
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Biology of the Interleukin-2 Receptor
1998Studies of the biology of the IL-2 receptor have played a major part in establishing several of the fundamental principles that govern our current understanding of immunology. Chief among these is the contribution made by lymphokines to regulation of the interactions among vast numbers of lymphocytes, comprising a number of functionally distinct ...
Dennis M. Willerford +2 more
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Interleukin-2, Interleukin-15, and Their Receptors
International Reviews of Immunology, 1998Both IL-15 and IL-2 are 14-15 kDa members of the four alpha-helical bundle family of cytokines that have T cell growth factor activity. In contrast to the pattern manifested by IL-2, IL-15 mRNA is produced by a wide variety of tissues other than T cells. We have demonstrated that IL-15 expression is posttranscriptionally regulated by multiple elements,
Thomas A. Waldmann +2 more
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Science, 1986
Antigen or mitogen-induced activation of resting T cells induces the synthesis of interleukin-2 (IL-2) as well as the expression of specific cell surface receptors for this lymphokine. Failure of the production of either IL-2 or its receptor results in a
T. Waldmann
semanticscholar +1 more source
Antigen or mitogen-induced activation of resting T cells induces the synthesis of interleukin-2 (IL-2) as well as the expression of specific cell surface receptors for this lymphokine. Failure of the production of either IL-2 or its receptor results in a
T. Waldmann
semanticscholar +1 more source
Interleukin-2 receptors in infectious mononucleosis
Immunology Letters, 1989The majority of peripheral blood mononuclear cells (PBMC) from acute-phase infectious mononucleosis (IM) patients express high levels of T10 (CD38) and HLA-DR surface antigens, which are markers characteristic of activated T cells. However, Tac antigen (p55) expression on these cells was not detectable by flow cytometric immunofluorescence, and only a ...
J M Ryan +5 more
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