Results 211 to 220 of about 122,014 (288)

A New Insight on Atherosclerosis Mechanism and Lipid-Lowering Drugs. [PDF]

Rev Cardiovasc Med
Li P, Jiang W.
europepmc   +1 more source

Associations Between Lipids and Lipid‐Lowering Drug Target Genes and Osteomyelitis: A Mendelian Randomization Analysis

Medicine Advances, EarlyView.
In this study, we identified several SNPs in PCSK9 as genetic tools to comprehensively assess the influential role of PCSK9 in CHD, CRP, and osteomyelitis. PCSK9 is associated with a lower risk of osteomyelitis, and PCSK9 is also associated with a reduction in CRP concentrations. Our study supports the notion that WC may be a potential mediator between
Zhiyi Zhou, Zhehan Yang, Junpan Chen, Minghao Wen, Jiayuan Lei, Wanzhe Liao, Yahan Li, Linghui Liu, Ziyuan Lu   +8 more
wiley   +1 more source

Clinical associations and potential cellular mechanisms linking G6PD deficiency and atherosclerotic cardiovascular disease. [PDF]

NPJ Metab Health Dis
Andrews PH, Zimring JC, McNamara CA.
europepmc   +1 more source

Xanomeline‐Trospium Chloride (Cobenfy): A New Era in Managing Schizophrenia—Comparative Effectiveness and Economic Challenges

Medicine Advances, EarlyView.
Xanomeline‐trospium chloride (cobenfy) is a muscarinic agonist used to treat hallucinations and psychotic illnesses such as Alzheimer's and Schizophrenia. It has been constructed for patients who are unable to tolerate dopamine‐targeting therapies and a comparison is drawn against other similar drugs with variables like cost, mechanism of action ...
Jawairya Muhammad Hussain, Wajiha Arif, Sharjeel Humayun, Nida Shoaib, Saim Mahmood Khan   +4 more
wiley   +1 more source

Research Progress on Anti-Hyperlipidemia Peptides Derived from Foods. [PDF]

Nutrients
Zhao M, Qiao K, Zhang L, Liang L, Chen S, Chen L, Zhang Y.   +6 more
europepmc   +1 more source

Regimes and Mechanisms of Inflammation Described by a Reaction–Diffusion System

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT Inflammation is a biological response of the immune system to external stimuli such as injury or infection. It plays an important role in various diseases including atherosclerosis, cancer, and neurodegenerative diseases. This work presents a generic inflammation model based on reaction–diffusion equations that describes the concentrations of ...
W. El Hajj, N. El Khatib, V. Volpert
wiley   +1 more source

Evolocumab Reduces Oxidative Stress and Lipid Peroxidation in Obese Zucker Rats. [PDF]

Pathophysiology
Cebova M, Bulkova R, Pechanova O.
europepmc   +1 more source

Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of Faecalibacterium prausnitzii in Overweight Adults–A Double‐Blind Trial

Molecular Nutrition &Food Research, EarlyView.
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina, Victor Nehmi Filho, Jéssica Alves de Freitas, Lucas Augusto Moysés Franco, Roberta Cristina Martins, Joyce Vanessa Fonseca, José Antônio Orellana Turri, Mariana Tedesco Hufnagel, Daniel Pecoraro Demarque, Bruna Fernanda Rio Branco da Silva, Arianne Fagotti Gusmão, Eloísa Helena Ribeiro Olivieri, Erica de Souza, Esther Alves de Souza, José Pinhata Otoch, Ana Flávia Marçal Pessoa   +15 more
wiley   +1 more source

Current usage of inclisiran for cardiovascular diseases: overview of current clinical trials. [PDF]

Front Pharmacol
Harbi MH.
europepmc   +1 more source

Mediterranean Diet Modulates Gene Expression of Cholesterol Efflux Receptors in High‐Risk Cardiovascular Patients

Molecular Nutrition &Food Research, EarlyView.
The graphical abstract (GA) displays the study of two randomized trials studying the molecular mechanisms of cholesterol efflux‐related genes analyzed via transcriptomics after two Mediterranean diet interventions. Cholesterol efflux molecules include ATP‐binding cassette transporters ABCA1 and ABCG1 in cholesterol transport to HDL. It also depicts the
Javier Hernando‐Redondo, Álvaro Hernáez, Albert Sanllorente, Xavier Pintó, Ramón Estruch, Jordi Salas‐Salvadó, Dolores Corella, Fernando Arós, Miguel Ángel Martínez‐González, Isaac Subirana, Daniel Muñoz‐Aguayo, Mireia Malcampo, Lluis Serra‐Majem, Dora Romaguera, Jose Lapetra, Emilio Ros, Francisco Tinahones, Rosa Maria Lamuela‐Raventós, Enrique Gómez‐Gracia, Montserrat Fitó, Olga Castañer   +20 more
wiley   +1 more source