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Ligand-Independent Spontaneous Activation of Purinergic P2Y<sub>6</sub> Receptor Under Cell Culture Soft Substrate. [PDF]
Nishimura A+7 more
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Pericyte pannexin1 controls cerebral capillary diameter and supports memory function. [PDF]
Mai-Morente S+6 more
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P2 purinergic receptor expression and function in tumor-related immune cells. [PDF]
Manoharan V, Adegbayi OO, Maynard JP.
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ATP and glutamate coordinate contractions in the freshwater sponge Ephydatia muelleri.
Ho VR, Goss GG, Leys SP.
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Current Opinion in Pharmacology, 2003
Activation of P2Y(1) and P2Y(12) receptors, through secreted ADP that is stimulated by agonists such as thrombin, thromboxane and collagen, is a major mechanism of platelet activation. P2X(1) receptors also participate in platelet shape change and potentiation of calcium mobilization.
Robert T. Dorsam+3 more
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Activation of P2Y(1) and P2Y(12) receptors, through secreted ADP that is stimulated by agonists such as thrombin, thromboxane and collagen, is a major mechanism of platelet activation. P2X(1) receptors also participate in platelet shape change and potentiation of calcium mobilization.
Robert T. Dorsam+3 more
openaire +3 more sources
Purinergic receptors in airway hydration
Biochemical Pharmacology, 2021Airway epithelial purinergic receptors control key components of the mucociliary clearance (MCC), the dominant component of pulmonary host defense. In healthy airways, the periciliary liquid (PCL) is optimally hydrated, thus acting as an efficient lubricant layer over which the mucus layer moves by ciliary force.
Eduardo R. Lazarowski+1 more
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Annals of the New York Academy of Sciences, 1990
In rabbits the contractile response of the urinary bladder is only partially due to cholinergic innervation since atropine does not completely block neuronally mediated contractions. In the human bladder this atropine resistance is controversial with some reporting atropine resistance in vitro while others have stated that the atropine resistance is ...
Michael R. Ruggieri+2 more
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In rabbits the contractile response of the urinary bladder is only partially due to cholinergic innervation since atropine does not completely block neuronally mediated contractions. In the human bladder this atropine resistance is controversial with some reporting atropine resistance in vitro while others have stated that the atropine resistance is ...
Michael R. Ruggieri+2 more
openaire +4 more sources
Signaling at Purinergic P2X Receptors
Annual Review of Physiology, 2009P2X receptors are membrane cation channels gated by extracellular ATP. Seven P2X receptor subunits (P2X1-7) are widely distributed in excitable and nonexcitable cells of vertebrates. They play key roles in inter alia afferent signaling (including pain), regulation of renal blood flow, vascular endothelium, and inflammatory responses.
Surprenant, Annmarie, Alan North, R.
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