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The enteric purinergic P2Y1 receptor
Current Opinion in Pharmacology, 2006Significant recent discoveries have shown that the P2Y(1) purinergic receptor subtype is expressed in the enteric nervous system and at intestinal neuromuscular junctions. Secretomotor neurons, which release vasoactive intestinal peptide at their junctions with intestinal secretory glands, express the P2Y(1) receptor.
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Purinergic receptors in embryonic and adult neurogenesis
Neuropharmacology, 2016ATP (adenosine 5'-triphosphate), one of the most ancient neurotransmitters, exerts essential functions in the brain, including neurotransmission and modulation of synaptic activity. Moreover, this nucleotide has been attributed with trophic properties and experimental evidence points to the participation of ATP-activated P2X and P2Y purinergic ...
Ágatha Oliveira +2 more
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Purinergic receptors and metabolic function
Drug Development Research, 1996Blood glucose concentration is a signal for the endocrine pancreas to release insulin or glucagon. Insulin lowers the level of glucose by inhibiting the hepatic glucose production and stimulating glucose utilization by skeletal muscles and adipocytes.
P. Petit +3 more
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Purinergic Receptors and Hepatobiliary Function
2003Publisher Summary This chapter describes the basic mechanisms that contribute to purinergic signaling in liver cells by focusing on a molecular and pharmacologic description of the receptors present, the mechanisms and regulation of adenosine triphosphate (ATP) release, and nucleotide/nucleoside degradation and reuptake pathways.
Andrew P. Feranchak, J. Gregory Fitz
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Is the benzodiazepine receptor purinergic?
European Journal of Pharmacology, 1979H.W. Damm +2 more
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Purinergic signaling in peripheral nervous system glial cells
Glia, 2021Jennifer Patritti-cram +2 more
exaly
From purines to purinergic signalling: molecular functions and human diseases
Signal Transduction and Targeted Therapy, 2021Alexei Verkhratsky +2 more
exaly
Purinergic Receptors in the Nervous System
2003Publisher Summary This chapter focuses on the localization and roles of purinergic receptor subtypes in the central nervous system (CNS), as comprehensive reviews of purinergic signaling in the peripheral nervous system. The concept of purinergic neurotransmission is the existence of postjunctional purinergic receptors. A basis for distinguishing two
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Astrocyte‐mediated purinergic signaling is upregulated in a mouse model of Fragile X syndrome
Glia, 2021Angela L Scott, Kathryn E Reynolds
exaly