P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]
, 2008 When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
King, Brian F., Wildman, Scott S.P.
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Pathophysiological role of extrasynaptic GABAA receptors in typical absence epilepsy [PDF]
, 2011 GABA is the principal inhibitory neurotransmitter in the mammalian CNS. It acts via two classes of receptors, the GABAA, a ligand gated ion channel (ionotropic receptor) and the metabotropic G-protein coupled GABAB receptor.
Errington, Adam C. +2 more
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Molecular pharmacology of AMPA receptor trafficking proteins - TARPs - evidence for an association with 5HT(_2c) receptors [PDF]
, 2009 There has been an increasing awareness of the involvement of neurotransmitters other than serotonin in depression, with new antidepressants possessing effects on other receptor types, such as Agomelatine®, an antagonist of 5HT(_2c) receptors that ...
Donoghue, Peter, Donoghue , Peter
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PREDICTING BOVINE SOMATOTROPIN USE BY CALIFORNIA DAIRY FARMERS [PDF]
An ex ante adoption model of bovine somatotropin (BST) is estimated with survey data of California milk producers. Theoretical justification is developed for incorporation of socioeconomic explanatory variables in a technology-adoption model.
Zepeda, Lydia
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Purinergic receptors in skeletal muscles in health and in muscular dystrophy [PDF]
, 2014 The P2 purinergic (nucleotide) receptor super-family comprises of two families of protein. The P2X, which are channel-forming ionotropic receptors and the P2Y metabotropic receptors activating G protein-mediated signalling pathways.
Young, Christopher +10 more
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Analysis of endogenous and recombinant bovine somatotropin in serum
, 2013 Within the EU the use of growth hormones is banned. However, in several countries outside the EU the use of the growth hormone somatotropin, a 191 amino acid protein, for cattle is allowed.
Merel A. Nessen +9 more
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Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity [PDF]
, 2003 A reduction in microglial activation and subsequent neurotoxicity may prove critical for neuroprotection in neurodegenerative diseases. We examined the expression and functionality of group III metabotropic glutamate (mGlu) receptors on microglia.
Taylor, D.L., Pocock, J.M., Diemel, L.T.
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Molecular pharmacological characterisation of recombinant and native NR2B- and NR3B- containing NMDA receptors [PDF]
, 2008 NMDA receptors are ionotropic, glutamate receptors which mediate fast excitatory transmissions within the central nervous system. They form tetrameric or pentameric heterologous complexes from seven NMDA receptor subunits NRl, NR2A-D and NR3A-B which ...
Chaffey, Heather Emily
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Receptor for activated C kinase-1 facilitates protein kinase C-dependent phosphorylation and functional modulation of GABA(A) receptors with the activation of G-protein-coupled receptors [PDF]
, 2002 GABA(A) receptors are the principal sites of fast synaptic inhibition in the brain. These receptors are hetero-pentamers that can be assembled from a number of subunit classes: alpha(1-6), beta(1-3), gamma(1-3), delta(1), epsilon, theta, and pi, but the ...
Trevor G Smart +7 more
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, 1987 Never before has there been so much controversy about a new drug as there is about Bovine Somatotropin (B.S.T.) This is even more unusual since the drug is only in the early period of its trials and is probably some four years away from being licensed ...
Baker, Ian D.
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