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TransTACs: Transforming antibodies into targeted protein degraders. [PDF]
Acta Pharm Sin BGuo Y, Che J, Dong X.
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Engineering baculo- and lentiviral vectors for enhanced and targeted gene delivery (Geeninsiirron tehostaminen ja kohdentaminen pintamuokatuilla bakulo- ja lentiviruksilla) [PDF]
Kaikkonen, Minna
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Transferrin and transferrin receptors update
Free Radical Biology and Medicine, 2019In vertebrates, transferrin (Tf) safely delivers iron through circulation to cells. Tf-bound iron is incorporated through Tf receptor (TfR) 1-mediated endocytosis. TfR1 can mediate cellular uptake of both Tf and H-ferritin, an iron storage protein. New World arenaviruses, which cause hemorrhagic fever, and Plasmodium vivax use TfR1 for entry into host ...
H. Kawabata
semanticscholar +4 more sources
TRANSFERRIN AND TRANSFERRIN RECEPTORS IN CARCINOMA OF THE BREAST
The Lancet, 1980Breast tissues from 59 patients were immunohistologically studied for transferrin and transferrin receptors. None of the 8 normal breasts or 22 benign mastopathies, and only 1 of 7 fibroadenomas were reactive for transferrin, but 16 (72.7%) of 22 carcinomas were positive and parallel sections showed histopathologically that the rective areas were ...
W. Page Faulk +2 more
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Current Drug Delivery, 2014
Anticancer therapeutic research aims to improve clinical management of the disease through the development of strategies that involve currently-relevant treatment options and targeted delivery.
Stephanie M. Tortorella, T. Karagiannis
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Anticancer therapeutic research aims to improve clinical management of the disease through the development of strategies that involve currently-relevant treatment options and targeted delivery.
Stephanie M. Tortorella, T. Karagiannis
semanticscholar +1 more source
Annual Review of Medicine, 1993
The transferrin receptor plays a critical role in iron metabolism by precisely contrOlling the flow of transferrin iron into body cells. A soluble truncated form of the receptor can be detected in human serum using sensitive immunoassays, and the initial clinical experience with this new measurement indicates that it reflects the total body mass of ...
Roy D. Baynes +2 more
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The transferrin receptor plays a critical role in iron metabolism by precisely contrOlling the flow of transferrin iron into body cells. A soluble truncated form of the receptor can be detected in human serum using sensitive immunoassays, and the initial clinical experience with this new measurement indicates that it reflects the total body mass of ...
Roy D. Baynes +2 more
openaire +3 more sources
Trends in Biochemical Sciences, 1982
Abstract The isolation and analysis of the transferrin receptor has been greatly aided by the use of monoclonal antibodies. The receptor is a disulphide-linked homo-dimer which spans the membrane and binds two molecules of transferrin. Controlling genes for this receptor in humans have been mapped to chromosome 3 using cell hybrids.
Laida Vodinelich +4 more
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Abstract The isolation and analysis of the transferrin receptor has been greatly aided by the use of monoclonal antibodies. The receptor is a disulphide-linked homo-dimer which spans the membrane and binds two molecules of transferrin. Controlling genes for this receptor in humans have been mapped to chromosome 3 using cell hybrids.
Laida Vodinelich +4 more
openaire +2 more sources
, 2016
A quartz crystal microbalance (QCM) biosensor was developed to detect highly metastatic breast cancer cells by functionalizing the gold sensor surface with transferrin attachment.
S. Atay +5 more
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A quartz crystal microbalance (QCM) biosensor was developed to detect highly metastatic breast cancer cells by functionalizing the gold sensor surface with transferrin attachment.
S. Atay +5 more
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Erythropoiesis and transferrin receptors
Current Opinion in Hematology, 2015The type 1 transferrin receptor (TfR1) is well known as a key player in erythroid differentiation through its role in iron uptake. Recently, it has been demonstrated that TfR1 could also have signaling functions in erythroid cells. Moreover, the second transferrin receptor, TfR2, whose signaling functions in hepatic cells are well established, was ...
Olivier Hermine +3 more
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Nanoscale, 2016
Among various cancers, pediatric brain tumors represent the most common cancer type in children and the second most common cause of cancer related deaths.
Shanghao Li +8 more
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Among various cancers, pediatric brain tumors represent the most common cancer type in children and the second most common cause of cancer related deaths.
Shanghao Li +8 more
semanticscholar +1 more source