Results 161 to 170 of about 10,909,684 (212)

Advanced Biological Therapies: Principles, Mechanisms and Medical Applications. [PDF]

J Clin Med
Brozek R, Lorenz A, Dorocka-Bobkowska B, Kurpisz M.   +3 more
europepmc   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Oncolytic myxoma virus and engineering strategies for advanced cancer immunotherapy. [PDF]

iScience
Trujillo Yeriomenko AD, Isaeva AS, Idota EE, Zhivoderov SP, Yurkov SG, Malogolovkin AS.   +5 more
europepmc   +1 more source

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor, E. N. Chow, M. Thomas, L. Johnson, A. Siefert, B. Wagner, J. B. Engiles, H. L. Reesink   +7 more
wiley   +1 more source

Goniothalamin as a Styryl-Lactone Toxicophore in Cancer Models: Electrophile-Driven DNA Damage, Reactive Oxygen Species-Endoplasmic Reticulum Stress Signaling and Detoxification-Relevant Safety Considerations. [PDF]

J Biochem Mol Toxicol
Joković N, Pešić S, Novaković M, Krstić AD, Setzer WN, Sharifi-Rad J, Calina D.   +6 more
europepmc   +1 more source

Anti‐Inflammatory Effects of Punicic Acid and Its Molecular Mechanisms in RAW264.7 Cells and Zebrafish

Food Safety and Health, EarlyView.
Punicic acid (PA) was enriched and purified from PSO by molecular distillation with significant anti‐inflammatory activity to RAW264.7 cells, as well as to zebrafish. Anti‐inflammatory mechanism involved regulating NF‐κB and MAPK signaling pathways. ABSTRACT Punicic acid (PA) is the main fatty acid in pomegranate seeds, which shows multiple biological ...
Mengqi Zhang, Caiyun Feng, Mengyao Zhu, Xu Guo, Yingying Chen, Wenwen Hu, Fei Dong, Jinyue Sun, Chao Liu   +8 more
wiley   +1 more source

Innate Immune Memory Responses in Organ Transplantation. [PDF]

Arterioscler Thromb Vasc Biol
de Jong LC, Rother N, Duivenvoorden R.
europepmc   +1 more source

Transcriptional circuits of the glioma microenvironment: FOSL2 as a master regulator of the pathological niche. [PDF]

Genes Dis
Zhang J, Guan C, Wang Z, Jin L, Lin Z, Wen J, Chen G, Guo P.   +7 more
europepmc   +1 more source

OX40 transcriptomic expression and its association with immune checkpoints and clinical outcomes. [PDF]

Ther Adv Med Oncol
Thapa B, Nishizaki D, Miyashita H, Lee S, Nesline MK, Previs RA, Conroy JM, Jensen TJ, DePietro P, Pabla S, Kato S, Kurzrock R.   +11 more
europepmc   +1 more source

Cell surface RNAs define a new interface for immune recognition. [PDF]

Front Immunol
Zhang X, Liao J, Chang Y, Shao X, Ma Y.
europepmc   +1 more source