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The Current Role of Antiangiogenics in Colorectal Cancer. [PDF]
Basile D +5 more
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Vascular endothelial growth factor: a key factor in the onset and treatment of depression. [PDF]
Wang J, Meng F, Wang L, Li Z.
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AdipoRon promotes angiogenesis in B-cell leukemia by modulating pro-angiogenic factors through AdipoR1. [PDF]
Mallardo M +4 more
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Mediterranean Diet as a Therapeutic Strategy for Hypertension and Cardiovascular Health. [PDF]
Liweleya S +10 more
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Vascular endothelial growth factor (VEGF) and its receptors
The FASEB Journal, 1999ABSTRACT Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular endothelial cells. Five VEGF isoforms are generated as a result of alternative splicing from a single VEGF gene. These isoforms differ in their molecular mass and in biological properties such as their ability to bind to ...
G. Neufeld +3 more
semanticscholar +3 more sources
Vascular endothelial growth factor and its receptors.
Cytokine & Growth Factor Reviews, 1996Vascular endothelial growth factor (VEGF) is a prime regulator of endothelial cell proliferation, angiogenesis, vasculogenesis and vascular permeability. Its activity is mediated by the high affinity tyrosine kinase receptors, KDR/Fik-1 and Fit-1. In this article, recently discovered structural, molecular and biological properties of VEGF are described.
M. Klagsbrun, P. D’Amore
semanticscholar +3 more sources
Signal transduction by vascular endothelial growth factor receptors.
Biochemical Journal, 2011VEGFs (vascular endothelial growth factors) control vascular development during embryogenesis and the function of blood vessels and lymphatic vessels in the adult. There are five related mammalian ligands, which act through three receptor tyrosine kinases. Signalling is modulated through neuropilins, which act as VEGF co-receptors.
S. Koch +4 more
semanticscholar +3 more sources
Signaling via vascular endothelial growth factor receptors.
Experimental Cell Research, 1999Angiogenesis, or development of blood vessels from preexisting vasculature, has important functions under both normal and pathophysiological conditions. Vascular endothelial growth factor receptors 1-3, also known as flt-1, KDR, and flt-4, are endothelial cell-specific receptor tyrosine kinases which serve as key mediators of the angiogenic responses ...
T. Petrova, T. Makinen, K. Alitalo
semanticscholar +3 more sources
Vascular Endothelial Growth Factor and its Receptors
Retina, 1994Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular endothelial cells and an angiogenic factor that is structurally related to platelet derived growth factor (PDGF). It is also known as the vascular permeability factor (VPF) because it efficiently potentiates the permeabilization of blood vessels. Five types of VEGF mRNA
G, Neufeld +4 more
openaire +2 more sources
Frontiers in Bioscience, 2007
Angiogenesis is a critical process in both physiological development and many pathological processes. Vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) signaling pathway plays a pivotal role in regulating angiogenesis. Many therapeutic agents targeting VEGF and VEGFR are currently in preclinical and clinical development.
Weibo, Cai, Xiaoyuan, Chen
openaire +2 more sources
Angiogenesis is a critical process in both physiological development and many pathological processes. Vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) signaling pathway plays a pivotal role in regulating angiogenesis. Many therapeutic agents targeting VEGF and VEGFR are currently in preclinical and clinical development.
Weibo, Cai, Xiaoyuan, Chen
openaire +2 more sources

