Results 291 to 300 of about 491,094 (347)

Ovarian vascular endothelial growth factor and vascular endothelial growth factor receptor patterns in reproductive aging

Fertility and Sterility, 2008
To investigate how levels of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) change during corpus luteum formation in reproductive aging.Adult and reproductive aging female rats were given pregnant mare serum gonadotropin (PMSG) and the ovaries and sera were collected at 0, 3, 5, and 7 days after human chorionic gonadotropin (hCG ...
John, Yeh, Beom Su, Kim, Jennifer, Peresie   +2 more
openaire   +2 more sources

Role of vascular endothelial growth factor receptor 1 and vascular endothelial growth factor receptor 2 in the vasodilator response to vascular endothelial growth factor in the neonatal piglet lung

Critical Care Medicine, 2005
Vascular endothelial growth factor (VEGF) regulates vascular proliferation and causes vasodilation. In the pulmonary circulation, the vasorelaxing effect of VEGF has been attributed to nitric oxide, whereas in other vascular beds, prostacyclin and other mechanisms are also involved. This vascular effect follows binding to two receptors, VEGF receptor 1
Annie, Janvier, Sophie, Nadeau, Johanne, Baribeau, Thérèse, Perreault   +3 more
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Role of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptors in Vascular Development

1999
Distinct cellular processes mediate blood-vessel formation during embryogenesis (Beck and D’Amore 1997; Carmeliet and Collen 1998a; Folkman and D’Amore 1996; Noden 1989; Risau 1997; Wilting and Christ 1996) (Fig. 1). Initially, mesodermal cells differentiate in situ into early haemangioblasts and form cellular aggregates (blood islands), in which the ...
P, Carmeliet, D, Collen
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Modulation of vascular endothelial growth factor receptors in melanocytes

Experimental Dermatology, 2005
Abstract:  Vascular endothelial growth factor (VEGF) is constitutively produced by keratinocytes, but has no known epidermal target cell. We now report that normal human melanocytes (Mc) maintained in serum‐free, hormone‐, and growth factor‐supplemented medium lacking phorbol ester and choleragen constitutively express VEGF receptor‐1 (VEGFR‐1), VEGFR ...
Ellen J, Kim, Hee-Young, Park, Mina, Yaar, Barbara A, Gilchrest   +3 more
openaire   +2 more sources

Angiosarcoma of the breast and vascular endothelial growth factor receptor.

Tumori, 2011
Breast angiosarcoma is rare and often associated with previous breast cancer treatment. The present study aimed to define long-term outcomes in relation to common prognostic factors. The expression of vascular endothelial growth factor receptor was also evaluated, as it may be a potential target for anti-angiogenic therapy.We retrospectively assessed ...
Massimiliano Gennaro, Barbara Valeri, Patrizia Casalini, Maria Luisa Carcangiu, Alessandro Gronchi, Alberto Rudy Conti, Roberto Agresti, Marco Greco   +7 more
openaire   +2 more sources

Vascular Endothelial Growth Factor Receptor-3

1999
Cell-cell communication during vascular development and tumour angiogenesis seems to involve at least five endothelial cell-specific tyrosine kinase receptors belonging to two distinct subclasses: two receptors of the Tie family, and three vascular endothelial cell growth factor receptors, VEGFR-1, -2 and -3, originally named Fltl (Fms-like tyrosine ...
J, Taipale, T, Makinen, E, Arighi, E, Kukk, M, Karkkainen, K, Alitalo   +5 more
openaire   +2 more sources

Inhibitors of the vascular endothelial growth factor receptor

Hematology/Oncology Clinics of North America, 2002
The inhibitors of VEGF-mediated signaling continue to wind their way through extensive preclinical and clinical development paths. Whereas the first phase III trial did not meet its endpoints, one hopes that the others will. As we learn more about the VEGF pathways in the laboratory and the clinic, we can interpret with greater certainty what role ...
openaire   +2 more sources

The vascular endothelial growth factor family and its receptors

Hematology/Oncology Clinics of North America, 2004
This article focuses on describing the biology of vascular endothelial growth factor (VEGF) and its receptors as well as the regulation of their expression. A thorough understanding of the VEGF system is paramount in optimizing antiangiogenic therapies as a component of antineoplastic regimens.
Alexander A, Parikh, Lee M, Ellis
openaire   +2 more sources

Increased vascular endothelial growth factor and receptors: relationship to angiogenesis in asthma.

American Journal of Respiratory and Critical Care Medicine, 2006
Increased vascularity is a feature of airway remodeling in asthma with the potential to contribute to a number of functional abnormalities in this chronic disease. Although various growth factors have been implicated in modulating vascularity, the important contributors in vivo are still being elucidated.
B. Feltis, D. Wignarajah, Ling Zheng, C. Ward, D. Reid, R. Harding, E. Walters   +6 more
semanticscholar   +4 more sources

Expression of Vascular Endothelial Growth Factor C and Vascular Endothelial Growth Factor Receptor 3 in Corneal Lymphangiogenesis

Experimental Eye Research, 2001
Lymphangiogenesis has been reported in vascularized corneas. However, the molecular mechanisms of lymphangiogenesis in the cornea are still unclear. Since lymphatic vessels may contribute to a decreased success rate of keratoplasty in vascularized cornea by accelerating antigen recognition and graft rejection, elucidation of the mechanisms of corneal ...
T, Mimura, S, Amano, T, Usui, Y, Kaji, T, Oshika, Y, Ishii   +5 more
openaire   +2 more sources