Results 91 to 100 of about 168,385 (341)

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

The Pre-Great Recession Slowdown in Productivity

open access: yes, 2015
In the years since the Great Recession, many observers have highlighted the slow pace of productivity growth around the world. For the United States and Europe, we highlight that this slow pace began prior to the Great Recession. The timing thus suggests
G. Cette, John G. Fernald, Benoît Mojon
semanticscholar   +1 more source

The U.S. Labor Market During and After the Great Recession: Continuities and Transformations

open access: yesRSF, 2017
The Great Recession of 2007–2009 created the largest economic upheaval in the United States since the Great Depression of the 1930s. Although economic downturns are a recurring phenomenon, the most recent recession was exceptional in its duration and ...
A. Kalleberg, Till M. von Wachter
semanticscholar   +1 more source

Will there be a worldwide recession? [PDF]

open access: yesIntereconomics, 1974
In recent weeks, fears of a worldwide economic recession have become widespread because more and more symptoms appear that resemble those at the start of the great depression of 1929. However, wrong conclusions may be drawn from similar symptoms unless basic development trends as well as the differences in overall data and in functional relations are ...
openaire   +2 more sources

Matrix: a complex amalgam of structures and functions in tumor microenvironment

open access: yesFEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis   +3 more
wiley   +1 more source

Hyperoxia Induced Alteration of Chromatin Structure in Human Bone Marrow Derived Primary Mesenchymal Stromal Cells

open access: yesAdvanced Biology, EarlyView.
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe   +4 more
wiley   +1 more source

What we know from the Last Two Economic Recessions. Lessons from the Romanian Experience [PDF]

open access: yesRomanian Economic Journal, 2018
Now, at the end of 2018, Romania enjoys its eighth consecutive year of robust economic growth after the last recession, which marked the years 2009-2010. Is it much? Is it time to once again expect a recession after seven good years?
Claudiu Doltu
doaj  

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

open access: yesAdvanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso   +5 more
wiley   +1 more source

THE RELATIONSHIP BETWEEN GLOBALIZATION AND THE ECONOMIC CRISIS

open access: yesUSV Annals of Economics and Public Administration, 2014
Since 2007, the whole world has been facing a very severe economic crisis. The most important economies of the world have been going through a period of deep recession. In this matter, globalization has had a major role.
Sabina TUCA
doaj  

SMALL BUSINESS – ALTERNATIVE TO UNEMPLOYMENT REDUCTION IN ECONOMY UNDER RECESSION [PDF]

open access: yesJournal of Process Management and New Technologies, 2013
The decade long trend of unemployment rate increase, reduction of national income and salaries of the employees and demand reduction implies the necessity for taking urgent measures and counteracting the high inflation rate in order to reduce the ...
Trajković Svetlana   +2 more
doaj  

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