Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy
Advanced Science, EarlyView.Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li +9 more
wiley +1 more source
Periodontally accelerated osteogenic orthodontics combined with i-PRF for the treatment of gingival recession: a case report with 5-year follow-up. [PDF]
BMC Oral HealthWang H, Zong J.
europepmc +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Advanced Science, EarlyView.Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
Soft Tissue Augmentation in Periodontics and Implantology: Current Concepts, Techniques, and Clinical Outcomes. [PDF]
CureusGandhi S, Kaushik M, Khattri S, Singh S.
europepmc +1 more source
Advanced Science, EarlyView.Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang +8 more
wiley +1 more source
Success in Gingival Recession Coverage: Prognostic Indicators From Private Practice. [PDF]
Int J DentSaminsky M +3 more
europepmc +1 more source
Advanced Science, EarlyView.Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou +10 more
wiley +1 more source
Initial postoperative alignment versus long-term outcomes in intermittent exotropia surgery. [PDF]
J AAPOSPediatric Eye Disease Investigator Group.
europepmc +1 more source
Advanced Science, EarlyView.Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang +10 more
wiley +1 more source
Comparison of root coverage by injectable-platelet rich fibrin in thick and thin phenotypes: a parallel-armed, prospective, preliminary clinical study with up to 48 months of follow-up. [PDF]
J Appl Oral SciAyyildiz BG, Terzioglu B, Eken S.
europepmc +1 more source