Results 61 to 70 of about 46,657 (265)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Статистика и экономика, 2016 The types of the unstable state of the macroeconomic environment affecting the strategy of forming government and business. Applied to high-tech industries studied forms of public-private partnerships.
Vyacheslav V. Baranov +3 more
doaj +1 more source
Poverty in the Time of COVID: The Effect of Social Assistance
LSE Public Policy Review, 2020 The global recession caused by COVID-19 will lead to the first increase in global poverty in decades. The extent of the increase in poverty depends on the availability and effectiveness of social assistance.
Nidhi Parekh, Oriana Bandiera
doaj +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Platelet-rich-fibrin: A novel root coverage approach
Journal of Indian Society of Periodontology, 2009 Treatment of gingival recession has become an important therapeutic issue due to increasing cosmetic demand. Multiple surgical procedures have been developed to obtain predictable esthetic root coverage.
Anilkumar K +5 more
doaj
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
The Biopolitics of Transactional Capitalism
MediaTropes, 2011 In the spring of 2010, major newspapers in the U.S. announced arrival of a “recovery” from the economic recession precipitated by the 2008 financial crisis.
Majia Holmer Nadesan
doaj
Analysis of the Role of Prosperity and Recession on Welfare in Iran: Compared to Oil and Non - Oil Production [PDF]
سیاستگذاری اقتصادیPurpose: The topic of welfare and its improvement is an important issue in different societies. According to the existing literature, there are multiple factors that affect the welfare status of countries, one of which is production and its fluctuations (
Mehdi Hasanpour Varkolaei +2 more
doaj +1 more source