Results 11 to 20 of about 112,812 (203)

Difluoro Carbenes: From Genuine Gold Complexes to Unprecedented Metallacyclic Reactivity. [PDF]

open access: yesAngew Chem Int Ed Engl
Thanks to chelating ligands and enhanced backdonation, genuine gold(I) difluorocarbenes persistent for hours at −30 °C or even 0 °C have been obtained. In addition to classical Fisher‐type electrophilic behavior, these complexes display unprecedented reactivity toward alkenes and 1,3‐dienes.
Vesseur D   +6 more
europepmc   +3 more sources

Sex Classification Based on the Functional Connectivity Patterns of the Language Network: A Resting State fMRI Study. [PDF]

open access: yesHum Brain Mapp
We classified the resting‐state functional connectivity patterns anchored to core regions of the language network in a large sample of healthy young adults. The results showed that these patterns contain information capable of predicting sex with an accuracy of 91.3% on the test set and 78.1% on the holdout set.
Lajoie X   +8 more
europepmc   +2 more sources

Modulation of succinyl-CoA:3-ketoacid CoA transferase activity by a single amino acid residue in acetate:succinate CoA transferase from Trypanosoma brucei, the causative agent of African sleeping sickness. [PDF]

open access: yesProtein Sci
Abstract Trypanosomatids are protozoan parasites that remain a global health challenge due to the limited efficacy, safety, and durability of current treatments. Acetate: succinate CoA transferase (ASCT), together with succinyl‐CoA synthase (SCS), forms the ASCT/SCS cycle that fuels ATP production and generates acetate, a central metabolic intermediate
Mochizuki K   +13 more
europepmc   +2 more sources

Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

open access: yesActa Neuropathologica Communications, 2018
Astrocyte reactivity and neuroinflammation are hallmarks of CNS pathological conditions such as Alzheimer’s disease. However, the specific role of reactive astrocytes is still debated.
Kelly Ceyzériat   +31 more
doaj   +1 more source

Essential oils of plants and their combinations as an alternative adulticides against Anopheles gambiae (Diptera: Culicidae) populations

open access: yesScientific Reports, 2022
The persistence of malaria and the increasing of resistance of Anopheles gambiae species to chemicals remain major public health concerns in sub-Saharan Africa.
Mahamoudou Balboné   +11 more
doaj   +1 more source

Thyroid Hormone Nuclear Receptor TRα1 and Canonical WNT Pathway Cross-Regulation in Normal Intestine and Cancer

open access: yesFrontiers in Endocrinology, 2021
A pivotal role of thyroid hormones and their nuclear receptors in intestinal development and homeostasis have been described, whereas their involvement in intestinal carcinogenesis is still controversial.
Maria Sirakov   +2 more
doaj   +1 more source

Anisotropy of the Upper Critical Field and Critical Current in Single Crystal MgB$_2$ [PDF]

open access: yes, 2002
We report on specific heat, high magnetic field transport and $ac-$susceptibility measurements on magnesium diboride single crystals. The upper critical field $H_{c2}$ for magnetic fields perpendicular and parallel to the Mg and B planes is presented for
A. G. M. Jansen   +42 more
core   +5 more sources

Using 31P-MRI of hydroxyapatite for bone attenuation correction in PET-MRI: proof of concept in the rodent brain

open access: yesEJNMMI Physics, 2017
Background The correction of γ-photon attenuation in PET-MRI remains a critical issue, especially for bone attenuation. This problem is of great importance for brain studies due to the density of the skull.
Vincent Lebon   +6 more
doaj   +1 more source

Confining Trypanosoma brucei in emulsion droplets reveals population variabilities in division rates and improves in vitro cultivation

open access: yesScientific Reports, 2021
Trypanosome parasites are infecting mammals in Sub-Saharan Africa and are transmitted between hosts through bites of the tsetse fly. The transmission from the insect vector to the mammal host causes a number of metabolic and physiological changes.
Simone H. Oldenburg   +7 more
doaj   +1 more source

Microbial degradation of a recalcitrant pesticide: chlordecone.

open access: yesFrontiers in Microbiology, 2016
Chlordecone (Kepone®) is a synthetic organochlorine insecticide (C10Cl10O) used worldwide mostly during the 1970s and 1980s. Its intensive application in the French West Indies to control the banana black weevil Cosmopolites sordidus led to a massive ...
Sébastien Chaussonnerie   +42 more
doaj   +1 more source

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