Results 101 to 110 of about 37,861 (303)

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

La recherche partenariale à l'UQAR : les formes en action : compte rendu de la journée d'étude organisée par le GRIDEQ et le CRDT-UQAR le 13 avril 2016 [PDF]

, 2017
La recherche partenariale prend une place de plus en plus importante dans le paysage scientifique. Se présentant sous une grande variété d’appellations (recherche-action, recherche collaborative, participative, recherche-intervention, etc.) (Dumais, 2011)
Alberio, Marco (dir.), Fortin, Marie-José (dir.), Rezelman, Abigaïl (dir.)   +2 more
core  

An Implanted Tooth That Can Feel

Advanced Science, EarlyView.
To endow the implanted tooth with masticatory perception, herein we demonstrate that a 3D‐printed piezoelectric‐core/robust‐sheath implanted tooth can rebuild the sensing feedback, serving as “mechanoreceptors” in converting the mechanical chewing force to electrical signals, and up to brain through surrounding alveolar nerve system.
Yaru Cao, Zhenhua Wu, Jiwei Sun, Ke Song, Jiayi Li, Yujin Li, Wenqi Chen, Hanyu Li, Shue Li, Cheng Yang, Silin Liu, Yunyun Han, Bin Su, Yumei Ding   +13 more
wiley   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Modeling multi-stakeholder forest management : the case of forest plantations in Sabah [PDF]

, 2005
The underlying decision theory of forest management changed from decisions made by the forest manager, a single stakeholder, to a decision-making process, which involves a variety of stakeholders with different goals.
Guizol, Philippe, Purnomo, Herry
core  

The Importance of Metal‐Organic Framework Linker Atoms for CO2 Reduction: A DFT Study

Advanced Science, EarlyView.
Using DFT, we examine the role of linker atoms in CO2 reduction on copper‐based metal organic frameworks (Cu MOFs). Our calculations reveal that linker atoms may serve as both CO2 and H‐shuttling sites and suggest linker electrostatics as a descriptor for linker activity. ABSTRACT Although the metal within the secondary building unit of a metal‐organic
Ugochukwu Nwosu, Samira Siahrostami
wiley   +1 more source

Un partenariat agriculteur - chercheur dans un programme de création de variété de coton au Bénin : bilan de trois années de sélection [PDF]

, 2001
La recherche béninoise a mis en place un programme d'amélioration génétique participative (AGP) en 1996 pour renforcer sa relation avec les organisations paysannes dans un contexte de libéralisation de la filière.
Assogba, Luc, Djaboutou, Mossibaou, Lançon, Jacques, Lewicki-Dhainaut, Sylvie, Orou Mousse, Bio Io, Sêkloka, Emmanuel, Takpara, Daouda   +6 more
core  

POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation

Advanced Science, EarlyView.
Schematic diagram of our study showing that highly expressed POU2F1 in colorectal cancer (CRC) can directly accelerate the cytosolic lactate export to decrease PPP1R11 lactylation at K59, thereby attenuating the E3 ligase enzyme activity and protein stability of PPP1R11, which inhibits the ubiquitination of MDR2 at K413 and K538 but increases the ...
Longzheng Xia, Jinguan Lin, Xianjie Jiang, Linda Oyang, Shiming Tan, Zongyao Ren, Qiu Peng, Qianjin Liao, Yujuan Zhou   +8 more
wiley   +1 more source

Recherche Culturelle et Sciences Participatives PARTICIP-ARC

, 2019
Suite à l’appel à manifestation d’intérêt lancé en 2017 par le ministère de la Culture, une trentaine de chercheurs et de professionnels du secteur culturel se sont réunis régulièrement pendant dix-huit mois pour partager leurs expériences et leurs réflexions sur la thématique « Recherche culturelle et sciences participatives ».
Chlous, Frédérique, Echassoux, Anna
openaire   +4 more sources

Verrouillages institutionnels des dynamiques d’innovation dans les systèmes agroforestiers structurés par les filières cacao et café en Haïti

Cahiers Agricultures
Cet article étudie les verrous de l’innovation dans les systèmes agroforestiers structurés par les filières cacao et café en Haïti, en questionnant l’environnement institutionnel qui régule leur régime sociotechnique. Il mobilise le cadre d’analyse multi-
Amazan Jean Fritzner, Temple Ludovic, Paul Bénédique   +2 more
doaj   +1 more source