Chronic Night Shift Is More Detrimental Than Chronic Light at Night on Circadian Rhythmicity and Metabolic Health in a Female Diurnal Rodent. [PDF]
To dissociate the effects induced by artificial indoor light at night from those induced by circadian desynchronization, females of the diurnal rodent, Arvicanthis ansorgei, were exposed to chronic indoor light at night (mimicking nightwork) or to chronic night shift (mimicking shiftwork).
Grosjean E +9 more
europepmc +2 more sources
Automated insulin delivery system use and physical activity levels in adults with type 1 diabetes: A BETTER registry analysis. [PDF]
Abstract Aims To explore the association between using automated insulin delivery (AID) systems and physical activity (PA) levels among people with type 1 diabetes. Methods Cross‐sectional study including 1156 participants from the BETTER Type 1 Diabetes registry.
Chahal T +10 more
europepmc +2 more sources
Exploring gender differences in physical activity and related barriers in children and adults living with type 1 diabetes: A narrative review. [PDF]
Abstract Aims In the general population, individuals who self‐identify as girls and women are typically less active and report more barriers to physical activity (PA), often influenced by gender stereotypes and sociocultural norms. These barriers may be accentuated in individuals with type 1 diabetes (T1D), who face additional diabetes‐related barriers
Heyman E +5 more
europepmc +2 more sources
Association between daily steps, diabetes management and health indicators in people living with type 1 diabetes: A cross-sectional study from the BETTER registry. [PDF]
Abstract Aims In people with type 1 diabetes, physical activity provides important health benefits but is mainly limited by fear of hypoglycaemia. Daily step count is a simple indicator of ambulatory activity. This study examined associations between step count and health indicators.
Garré TI +9 more
europepmc +2 more sources
Limited impact of the PEP1 structured physical activity program on perceived barriers to physical activity in people living with type 1 diabetes. [PDF]
Diabetic Medicine, Volume 42, Issue 7, July 2025.
Guédet C +6 more
europepmc +2 more sources
Caffeine exacerbates exercise-induced gut cell damage and is influenced by ADORA2A genotype but not CYP1A2 genotype: A preliminary study. [PDF]
Abstract Endurance exercise may be associated with acute damage to intestinal epithelial cells. The effect of caffeine supplementation, and whether this is influenced by common genetic polymorphisms (ADORA2A: rs5751876 and CYP1A2: rs762551), is not currently known.
Davison G +3 more
europepmc +2 more sources
Continental Patterns of Phenotypic Variation Along Replicated Urban Gradients: A Mega-Analysis. [PDF]
Using a mega‐analysis approach with long‐term data from 21 urban and nonurban great and blue tit populations, we introduce and test hypotheses to determine how urbanisation affects tarsus length and lay date variation at different population levels. We find that urbanisation is associated with increases in phenotypic variation within subpopulations by ...
Thompson MJ +23 more
europepmc +2 more sources
Nanomaterials Trigger Functional Anti-Tumoral Responses in Primary Human Immune Cells. [PDF]
Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Mittelheisser V +20 more
europepmc +2 more sources
Sepsis Induces Long-Term Muscle and Mitochondrial Dysfunction due to Autophagy Disruption Amenable by Urolithin A. [PDF]
ABSTRACT Background Sepsis survivors often experience sustained muscle weakness, leading to physical disability, with no pharmacological treatments available. Despite these well‐documented long‐term clinical consequences, research exploring the cellular and molecular mechanisms is sorely lacking.
Pierre A +27 more
europepmc +2 more sources
Early sensorimotor restriction in rats induces age-dependent mitochondrial alterations in skeletal muscles and brain structures. [PDF]
Abstract figure legend This study aimed to determine whether early sensorimotor restriction (SMR) alters mitochondrial enzyme activities in rat muscles and brain structures. SMR was induced via immobilizing the hind limbs of pups for 16 h per day during the dark phase from birth to postnatal day (PND) 28.
Van Gaever M +4 more
europepmc +2 more sources

