Results 91 to 100 of about 385,123 (297)
Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
Calcium sensors as key hubs in plant responses to biotic and abiotic stresses
The Ca2+ ion is recognized as a crucial second messenger in signalling pathways coupling the perception of environmental stimuli to plant adaptive responses.
Benoît eRanty +5 more
doaj +1 more source
Resolving the Structural Duality of Graphene Grain Boundaries
Cantilever ncAFM resolves the atomic structure of grain boundaries in graphene, revealing coexisting stable and metastable types. Both contain pentagon/heptagon defects, but metastable GBs show irregular geometries. Modeling shows metastable GBs form under compression, exhibiting vertical corrugation, while stable GBs are flat.
Haojie Guo +11 more
wiley +1 more source
The Asian tiger mosquito Aedes (Stegomya) albopictus is an invasive species that has spread across the world in the last two decades, showing a great capacity to adapt to contrasting climates and environments.
Guillaume eMinard +5 more
doaj +1 more source
Cosmological evolution in a brane-universe
The idea of extra-dimensions has recently gone through a renewal with the hypothesis, suggested by recent developments in string theory, that ordinary matter is confined to a sub-space, called brane, embedded in a higher dimensional spacetime.
Langlois, David
core +1 more source
Solvent‐Free Thermal Defect Engineering in Molecular Frameworks With Volatile Linkers
Thermal removal of neutral volatile linkers enables precise and solvent‐free generation of metal vacancies in MOFs. This strategy affords redox‐stable, coordinatively unsaturated FeII sites with tunable spin, ligand coordination, and catalytic behavior. The approach offers a general route to design defect‐functional materials through local coordination
Sonia Martínez‐Giménez +9 more
wiley +1 more source
The original version of this article incorrectly listed an affiliation of Sara Bonacchi as ‘Present address: Institut National de la Recherche Scientifique (INRS), EMT Center, Boulevard Lionel-Boulet, Varennes, QC, J3X 1S2, 1650, Canada’, instead of the ...
Marco Gobbi +13 more
doaj +1 more source
Healthy oysters are inhabited by abundant microbial communities that vary with environmental conditions and coexist with immunocompetent cells in the circulatory system.
Paulina eSchmitt +5 more
doaj +1 more source
An L0 dwarf companion in the brown dwarf desert, at 30 AU
We present the discovery of an L0 companion to the nearby M1.5 dwarf G 239-25, at a projected distance of 31 AU. It is the faintest companion discovered so far in our adaptive optics survey of all known M dwarfs within 12 pc, and it lies at the stellar ...
A. Manchado +42 more
core +1 more source
Ordered three‐dimensional anodic aluminum oxide (3D‐AAO) nanoarchitectures with longitudinal and transverse pores enable architecture‐driven metamaterials. The review maps fabrication advances, including hybrid pulse anodization, and shows how 3D‐AAO templates tailor properties across magnetism, energy, catalysis, and sensing.
Marisol Martín‐González
wiley +1 more source

