Discovery of a Reversible Sub‐Picomolar Thrombin Inhibitor Using DCC
An ultrapotent yet fully reversible trivalent thrombin inhibitor discovered through screening a large dynamic combinatorial library (DCL) of 125 000 members of self‐assembled fragments. The innovative approach leverages size‐exclusion‐based affinity selection, coupled with MALDI‐TOF mass spectrometry readout, enabling the full workflow to be completed ...
Millicent Dockerill +2 more
wiley +2 more sources
Author Correction: Mechanism of trans-envelope bacterial polysaccharide secretion in Class-3 outer-membrane polysaccharide export (OPX) protein systems. [PDF]
Mellouk A +7 more
europepmc +1 more source
On‐Demand Deconstructable Thermosets Through Cleavable Comonomer and Thermolatent Base Synergy
Thermosets, valued for their chemical and mechanical properties, resist recycling due to their cross‐linked structure. Weak bonds via comonomers enable degradability, but diffusion limits effectiveness. We incorporate thermolatent bases before polymerization (thermal or 3D‐VAT printing).
Sophia Kouider +15 more
wiley +2 more sources
Redox Control in a Conducting MOF through Coupled Electronic-Vibronic Effects. [PDF]
Rambabu D +15 more
europepmc +1 more source
Chlorine‐Free Depolymerization of Commercial PMMA via Oxygen‐Centered Radicals
A new chlorine‐free photothermal method enables sustainable recycling of plastics with C–C backbones under mild conditions. Driven by an oxygen‐centered radical pathway with ppm levels of anthraquinone catalyst, it eliminates hazardous chlorinated solvents, achieving an impressive 97% depolymerization conversion.
Chih‐Yin Lin +5 more
wiley +2 more sources
Expanded applicability of the triple oxygen isotope composition of phytoliths as an indicator of atmospheric relative humidity. [PDF]
Alexandre A +5 more
europepmc +1 more source
Our synthetic endeavor toward the total synthesis of the reported unprecedented tricyclic skeleton of the sesquiterpene pestalustaine A allowed us to perform divergent cyclizations of a bicyclo[4.4.1]undec‐3‐ene into complex tricyclic architectures and to revise the structure of the natural product.
Wei Cao +12 more
wiley +2 more sources
Scientific evidence does not support oyster farming as a marine carbon dioxide removal strategy for climate mitigation. [PDF]
Pernet F +8 more
europepmc +1 more source
Conférence : Recherche scientifique versus « recherche en travail social »
openaire +1 more source
1,2‐Aryl migration involving in situ‐generated alkyl iodine(III) species proceeds through a previously unrecognized 1,2‐C/I(III) dyotropic rearrangement. Migratory aryl fluorination, acetoxylation, and alkoxylation of 2‐alkyl‐2‐aryl‐3‐iodopropanoates provide α‐heterofunctionalized products, accompanied by aryl migration from the α‐ to the β‐position ...
Chen‐Xu Liu +3 more
wiley +2 more sources

