Results 151 to 160 of about 61,898 (257)

Reply to Peigneur et al. The Helix Ring Peptide U11 from the Venom of the Ant, Tetramorium bicarinatum, Acts as a Putative Pore-Forming Toxin, Not a New Kv1.3 Channel Blocker. Comment on "Boy et al. A New Kv1.3 Channel Blocker from the Venom of the Ant Tetramorium bicarinatum. Toxins 2025, 17, 379". [PDF]

Toxins (Basel)
Boy G, Jouvensal L, Téné N, Carayon JL, Bonnafé E, Paquet F, Treilhou M, Loth K, Billet A.   +8 more
europepmc   +1 more source

Proteinvermittelte Kupfer‐Redoxregulation: Rolle von Disulfidbrücken und allosterischer Modulation

Angewandte Chemie, EarlyView.
Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann, Chang Liu, Xue Wang, Hegne Pupart, Xun Sun, Jan Gui‐Hyon Dreiser, Peep Palumaa, Qinghua Liao, Matthias Krack, Jinghui Luo   +9 more
wiley   +1 more source

Total Synthesis of the Spirocyclic Bis‐Indole Alkaloid (−)‐Owerreine via a [4+2] Annulation

Angewandte Chemie, EarlyView.
The total synthesis of the bis‐indole alkaloid (−)‐owerreine has been accomplished by a diastereoselective [4+2] annulation between an enamine and an α,β−unsaturated indolenine precursor to form the 3‐spirocyclic tetrahydropyridine linkage of the natural product. DFT calculations allow an understanding of the mechanism of the key annulation.
Elisa Coll, Vincent Gandon, Cyrille Kouklovsky, Laurent Evanno, Guillaume Vincent   +4 more
wiley   +2 more sources

Multiannual environmental forcing shapes breeding phenology and success in a sub-Antarctic seabird. [PDF]

Sci Adv
Bardon G, Barracho T, Durant JM, Lecomte N, Le Maho Y, Stenseth NC, Cristofari R, Le Bohec C.   +7 more
europepmc   +1 more source

One‐Pot Amidation/C─H Halogenation by an Efficient Electrochemical Cascade

Angewandte Chemie, EarlyView.
A sustainable electrochemical cascade enables the one‐pot synthesis of regioselectively halogenated N‐aryl amides from readily available amines and acyl halides under mild conditions. The method merges amidation and C─H halogenation in a single operational step, delivering broad substrate scope, high selectivity, and scalability, and provides an ...
Sudipta Ponra, Ruzal Sitdikov, Hasil Aman, Alyssio Calis, Gergely Laczkó, Virgile Rouffeteau, Maxime R. Vitale, Imre Pápai, Oscar Verho   +8 more
wiley   +2 more sources

Exploratory assessment of phosphorylated TDP-43 immunoreactivity in minor salivary glands of patients with ALS. [PDF]

Acta Neuropathol Commun
Garnier M, Gouju J, Rousseau A, Zidane-Marinnes M, Scherer C, Cassereau J, Letournel F, Codron P.   +7 more
europepmc   +1 more source

Editorial commitment to trust and integrity in science: implications for pain and anesthesiology research. [PDF]

Can J Anaesth
Palermo TM, Bouhassira D, Davis KD, Hemmings HC, Hurley RW, Katz J, Pandit JJ, Price TJ, Schatman ME, Schwarz SKW, Turk DC, Van de Velde M, Wiles MD, Yaksh TL, Yarnitsky D.   +14 more
europepmc   +1 more source

Scientific integrity from a meta-ethical perspective: more contextualization and research ethics committees? A preliminary meta-ethics study. [PDF]

BMC Res Notes
Stoeklé HC, Lasterie R, Hervé C.
europepmc   +1 more source

Biomechanical analysis of surgical alignment and design in total knee arthroplasty. [PDF]

Arch Orthop Trauma Surg
Innocenti B, Bori E.
europepmc   +1 more source

Effects of a bloodless diet on fitness and malaria susceptibility in Anopheles mosquitoes from Burkina Faso. [PDF]

Sci Rep
de Sales Hien DF, Sare I, Sib AMAP, Poda BS, Velez R, Marques J, Silveira H, Diabate A, Bilgo EM.   +8 more
europepmc   +1 more source