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Bioorthogonal CRISPR/Cas9‐Drug Conjugate: A Combinatorial Nanomedicine Platform
Advanced Science, Volume 10, Issue 27, September 26, 2023., 2023 Here, a nanomedicine platform based on bioorthogonal CRISPR/Cas9‐drug conjugates, which can be self‐delivered in vivo and exert strong anti‐tumor effects upon gene editing and chemotherapy is developed. The current development provides a powerful strategy that can be widely applied for the therapy of human diseases such as cancer and genetic disorders.
Marcel Janis Beha +9 more
wiley +1 more source
CRISPR/Cas9 System: A Bacterial Tailor for Genomic Engineering
Genetics Research International, Volume 2018, Issue 1, 2018., 2018 Microbes use diverse defence strategies that allow them to withstand exposure to a variety of genome invaders such as bacteriophages and plasmids. One such defence strategy is the use of RNA guided endonuclease called CRISPR‐associated (Cas) 9 protein.
Bilal Ahmad Lone +5 more
wiley +1 more source