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Bioorthogonal CRISPR/Cas9‐Drug Conjugate: A Combinatorial Nanomedicine Platform
Here, a nanomedicine platform based on bioorthogonal CRISPR/Cas9‐drug conjugates, which can be self‐delivered in vivo and exert strong anti‐tumor effects upon gene editing and chemotherapy is developed. The current development provides a powerful strategy that can be widely applied for the therapy of human diseases such as cancer and genetic disorders.
Marcel Janis Beha+9 more
wiley +1 more source